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Creating clinical and biomedical Understanding through Research Evidence –

For the ethical study of ME/CFS


CURE-ME is the ME/CFS research team at the London School of Hygiene & Tropical Medicine (LSHTM). CURE-ME's UK ME/CFS Biobank project is overseen by a Steering Group (pictured below).

What is Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS)?

ME/CFS is a long-term disabling medical condition usually presenting with severe and overwhelming fatigue after mental or physical activity. This is accompanied by a range of disabling symptoms such as cognitive impairment, sleep problems, pain, and autonomic dysfunction, which follow abnormalities in the nervous and immunological systems. In the UK, ME/CFS affects at least one in every 500 people, with a much larger number of people having other forms of chronic fatigue (non-ME chronic fatigue).

Although some people with ME/CFS will recover after a period of time, many will endure long-term disease and disability, which in about 25% of cases can be severe enough to force the person to remain housebound or bedbound. There is currently no curative treatment for ME/CFS.

Our Research

Our research has focussed on improving recognition, diagnosis and treatment of ME/CFS, from the National CFS/ME Observatory, which explored the impact on affected individuals, to most recently, the development of the UK’s first biobank of samples for ME/CFS research.

The CURE-ME ME/CFS research team is at the forefront of participative epidemiological and qualitative research on ME/CFS and of the identification and long-term follow-up of well-characterised cases of ME/CFS as well as of healthy controls, for comparison purposes, for clinical and biomedical research.

Our research group is based at the Disability Centre, which is part of the Clinical Research Department in the Faculty of Infectious and Tropical Diseases (ITD). 

Research group

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