Dr Deborah Watson-Jones BSc BMBCh MRCP(UK) DTM&H PhD

Senior Lecturer (Clinical)

• Affiliation
• Teaching
• Research
• Publications

• 
• Mwanza Intervention Trials Unit
• National Institute for Medical Research
• Mwanza
• P.O. Box 11936
• T: +255 754 056066
• F: +255 28 2500019

Debby Watson-Jones is a Clinical Epidemiologist who has lived and worked in Kenya, Nigeria, Senegal, India, Mongolia and Tanzania. She has worked for LSHTM since 1995 and is currently based in Tanzania.

Affiliation

• Department of Clinical Research

Teaching

She is the co-organiser of Control of Reproductive Tract Infections/Sexually Transmitted Infections Module (3192) and has taught on the HIV and STD component of MSc in Control of Infectious Diseases and on Foundations in Reproductive Health, Safe Motherhood and the AIDS study units and on HIV/STD Control in Conflicts for the Health in Complex Emergencies Course.

Research

Her main research interest is the development and evaluation of interventions to control HIV and sexually transmitted infections in sub-Saharan Africa. She is currently leading a trial to compare different delivery strategies for the human papillomavirus (HPV) vaccine in Tanzania and studies on the epidemiology of HPV in Tanzanian girls and is working on a trial of combination HIV prevention, including immediate lifelong ART in HIV infected individuals, in Zambia and South Africa (the PopART trial).

Recently completed studies include a phase IIIb trial of GSK's bivalent HPV vaccine to assess vaccine immunogenicity and safety in young African women, an intervention trial against HSV-2 to reduce HIV incidence and HIV shedding in high risk women from goldmining communities in NW Tanzania and operational research on PMTCT programme performance in Tanzania and Kenya.  She has also been involved in a study to evaluate the impact of adolescent sexual & reproductive health intervention in Tanzania (the MEMA kwa Vijana trial) and in microbicides research in Tanzania (the Pro2000 phase III trial). Her previous studies include research on hydatid disease in Kenya and Mongolia, and on syphilis prevention in pregnancy in Mwanza, Tanzania and HIV/STD control in large-scale goldmines and neighbouring communities in the Lake Victoria Goldfields. She was the LSHTM research team leader in Mwanza from 2003-2007.

She has been a temporary advisor for the WHO HPV Vaccine Advisory Committee and is part of the WHO  Committee for the revision of guidelines for comprehensivce cervical cancer control (C4-GEP).

 

 

• Selected publications

• Patient attrition between diagnosis with HIV in pregnancy-related services and long-term HIV care and treatment services in Kenya: A retrospective study.

  Ferguson, L. ; Lewis, J. ; Grant, A.D. ; Watson-Jones, D. ; Vusha, S. ; Ong?ech, J.O. ; Ross, D.A. ;

  J Acquir Immune Defic Syndr, 2012;

• Patterns of herpes simplex virus shedding over 1 month and the impact of acyclovir and HIV in HSV-2-seropositive women in Tanzania.

  Tanton, C.; Weiss, H.A.; LeGoff, J.; Changalucha, J.; Clayton, T.C.; Ross, D.A.; Belec, L.; Hayes, R.J.; Watson-Jones, D.;

  Sex Transm Infect, 2011; 87(5):406-11

• Risk factors for HIV incidence in women participating in an HSV suppressive treatment trial in Tanzania

  Watson-Jones, D.; Baisley, K.; Weiss, H.A.; Tanton, C.; Changalucha, J.; Everett, D.; Chirwa, T.; Ross, D.; Clayton, T.; Hayes, R.

  AIDS, 2009; 23(3):415-422

• Effect of Herpes Simplex Suppression on Incidence of HIV among Women in Tanzania.

  Watson-Jones, D.; Weiss, H.A.; Rusizoka, M.; Changalucha, J.; Baisley, K.; Mugeye, K.; Tanton, C.; Ross, D.; Everett, D.; Clayton, T.; Balira, R.; Knight, L.; Hambleton, I.; Le Goff, J.; Belec, L.; Hayes, R.;

  N Engl J Med, 2008; 358(15):1560-71

• Risk Factors for Herpes Simplex Virus Type 2 and HIV Among Women at High Risk in Northwestern Tanzania: Preparing for an HSV-2 Intervention Trial.

  Watson-Jones, D.; Weiss, H.A.; Rusizoka, M.; Baisley, K.; Mugeye, K.; Changalucha, J.; Everett, D.; Balira, R.; Knight, L.; Ross, D.; Hayes, R.J.;

  J Acquir Immune Defic Syndr, 2007; 46(5):631-642

• Is antenatal syphilis screening still cost effective in sub-Saharan Africa

  Terris-Prestholt, F.; Watson-Jones, D.; Mugeye, K.; Kumaranayake, L.; Ndeki, L.; Weiss, H.; Changalucha, J.; Todd, J.; Lisekie, F.; Gumodoka, B.; Mabey, D.; Hayes, R.

  Sexually Transmitted Infections, 2003; 79(5):375-81

• Syphilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancy

  Watson-Jones, D.; Changalucha, J.; Gumodoka, B.; Weiss, H.; Rusizoka, M.; Ndeki, L.; Whitehouse, A.; Balira, R.; Todd, J.; Ngeleja, D.; Ross, D.; Buve, A.; Hayes, R.; Mabey, D.

  Journal of Infectious Diseases, 2002; 186(7):940-7

• Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomes

  Watson-Jones, D.; Gumodoka, B.; Weiss, H.; Changalucha, J.; Todd, J.; Mugeye, K.; Buve, A.; Kanga, Z.; Ndeki, L.; Rusizoka, M.; Ross, D.; Marealle, J.; Balira, R.; Mabey, D.; Hayes, R.

  Journal of Infectious Diseases, 2002; 186(7):948-57

• → View all Dr Deborah Watson-Jones's publications

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