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Dr Steve Walker

PhD MRCP(UK) DTM&H

Associate Professor

I am a Consultant Dermatologist and Associate Professor in the Department of Clinical Research. I trained in dermatology at Glasgow, London and Manchester in the United Kingdom and at Harvard University in the USA. I completed my PhD thesis: "The measurement, treatment and immunopathology of leprosy Type 1 reactions" under the supervision of Professor Diana Lockwood at LSHTM.
I work as a consultant dermatologist in the United Kingdom seeing NHS patients with a wide range of skin disorders.
My main research interests are the pathophysiology and managment of leprosy reactions, cutaneous infection, scabies and other ectoparasitic skin disorders and the epidemiology of skin disease.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Teaching

I teach on a variety of LSHTM courses both MSc and the Diplomas in Tropical Medicine and Hygiene.
I also lecture students studying for the MSc in Clinical Dermatology at King's College London and the MSc in International Health at the Charité - Universitätsmedizin Berlin.

Research

I am the coordinator of the Erythema Nodosum Leprosum International STudy (ENLIST) Group. Erythema nodosum leprosum (ENL) is a severe complication of leprosy. We are clinicians, statisticians and laboratory scientists with extensive clinical and research experience in the diagnosis and management of leprosy and its complications.
We are based at institutions in seven countries on four continents. The group is coordinated from London and includes centres in Bangladesh, Brazil, Ethiopia, India, Indonesia, Nepal and the Philippines. The ENLIST Group aims to improve: the understanding of the mechanisms which cause ENL, the evidence to guide treatment decisions and the access to effective treatments.
I am also the co-PI on a study of scabies outbreaks in UK residential care facilities. This study is a collaboration with researchers from the Brighton and Sussex Medical School and Public Health England.

 

 

 

Research Area
Clinical guidelines
Clinical trials
Parasites
Global Health
Medicines
Outbreaks
Discipline
Medicine
Disease and Health Conditions
Infectious disease
Leprosy
Neglected Tropical Diseases (NTDs)
Skin disease
Tropical diseases
Country
Bangladesh
Brazil
Ethiopia
Indonesia
India
Nepal
Philippines
Region
East Asia & Pacific (all income levels)
Latin America & Caribbean (all income levels)
South Asia
Sub-Saharan Africa (developing only)

Selected Publications

ENLIST 1: An International Multi-centre Cross-sectional Study of the Clinical Features of Erythema Nodosum Leprosum.
Walker, S.L. ; Balagon, M. ; Darlong, J. ; Doni, S.N. ; Hagge, D.A. ; Halwai, V. ; John, A. ; Lambert, S.M. ; Maghanoy, A. ; Nery, J.A. ; Neupane, K.D. ; Nicholls, P.G. ; Pai, V.V. ; Parajuli, P. ; Sales, A.M. ; Sarno, E. ; Shah, M. ; Tsegaye, D. ; Lockwood, D.N. ; Erythema Nodosum Leprosum International STudy Group, . ;
PLoS Negl Trop Dis
The mortality associated with erythema nodosum leprosum in ethiopia: a retrospective hospital-based study.
Walker, S.L. ; Lebas, E. ; Doni, S.N. ; Lockwood, D.N. ; Lambert, S.M. ;
PLoS Negl Trop Dis
Skin disorders affecting human immunodeficiency virus-infected children living in an orphanage in Ethiopia.
Doni, S.N. ; Mitchell, A.L. ; Bogale, Y. ; Walker, S.L. ;
Clin Exp Dermatol
The effect of systemic corticosteroid therapy on the expression of toll-like receptor 2 and toll-like receptor 4 in the cutaneous lesions of leprosy Type 1 reactions.
Walker, S.L. ; Roberts, C.H. ; Atkinson, S.E. ; Khadge, S. ; Macdonald, M. ; Neupane, K.D. ; Ranjit, C. ; Sapkota, B.R. ; Dhakal, S. ; Hawksworth, R.A. ; Mahat, K. ; Ruchal, S. ; Hamal, S. ; Hagge, D.A. ; Lockwood, D.N. ;
Br J Dermatol
A Phase Two Randomised Controlled Double Blind Trial of High Dose Intravenous Methylprednisolone and Oral Prednisolone versus Intravenous Normal Saline and Oral Prednisolone in Individuals with Leprosy Type 1 Reactions and/or Nerve Function Impairment.
Walker, S.L. ; Nicholls, P.G. ; Dhakal, S. ; Hawksworth, R.A. ; Macdonald, M. ; Mahat, K. ; Ruchal, S. ; Hamal, S. ; Hagge, D.A. ; Neupane, K.D. ; Lockwood, D.N. ;
PLoS Negl Trop Dis
Development and validation of a severity scale for leprosy type 1 reactions.
Walker, S.L.; Nicholls, P.G.; Butlin, C.R.; Nery, J.A.; Roy, H.K.; Rangel, E.; Sales, A.M.; Lockwood, D.N.;
PLoS Negl Trop Dis
Skin disease is common in rural Nepal: results of a point prevalence study.
Walker, S.L.; Shah, M.; Hubbard, V.G.; Pradhan, H.M.; Ghimire, M.;
Br J Dermatol
See all Dr Steve Walker's Publications