Dr Esmeralda Valiente PhD
- Room 380
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: +44 (0)02079588381
I obtained my PhD in 2008 at the University of Valencia (Spain). In this work, I obtained several mutants, investigating the role of different virulence factors of Vibrio vulnificus. Furthermore, I researched the pathogenesis of vibriosis and quorum sensing in Vibrio vulnificus.
Affiliation
Teaching
I am tutoring and teaching on the distance learning MSc course in Infectious Diseases, Biology of Infectious Diseases module. I also supervise Masters students in the lab.
Research
I joined the school in October 2008 to study genetic and phenotypic aspects of emerging virulent Clostridium difficile strains.
Research areas
- Bacteria
Disciplines
- Genetics
- Genomics
- Microbiology
- Molecular biology
Disease and Health Conditions
- Infectious disease
Other interests
- Clostridium Difficile
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Selected publications
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Emergence of new PCR-ribotypes from the hypervirulent Clostridium difficile 027 lineage.
Valiente, E.; Dawson, L.F.; Cairns, M.D.; Stabler, R.A.; Wren, B.W.;
J Med Microbiol, 2011;
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Glycoproteomics: a powerful tool for characterizing the diverse glycoforms of bacterial pilins and flagellins.
Hitchen, P.G.; Twigger, K.; Valiente, E.; Langdon, R.H.; Wren, B.W.; Dell, A.;
Biochem Soc Trans, 2010; 38(5):1307-13
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In-depth genetic analysis of Clostridium difficile PCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions.
Stabler, R.A. ; Valiente, E. ; Dawson, L.F. ; He, M. ; Parkhill, J. ; Wren, B.W. ;
Gut Microbes, 2010; 1(4):269-276
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Clostridium difficile - a continually evolving and problematic pathogen.
Dawson, L.F.; Valiente, E.; Wren, B.W.;
Infect Genet Evol, 2009; 9(6):1410-7
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Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium.
Stabler, R.A.; He, M.; Dawson, L.; Martin, M.; Valiente, E.; Corton, C.; Lawley, T.D.; Sebaihia, M.; Quail, M.A.; Rose, G.; Gerding, D.N.; Gibert, M.; Popoff, M.R.; Parkhill, J.; Dougan, G.; Wren, B.W.;
Genome Biol, 2009; 10(9):R102
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Role of the metalloprotease Vvp and the virulence plasmid pR99 of Vibrio vulnificus serovar E in surface colonization and fish virulence.
Valiente, E.; Lee, C.T.; Hor, L.I.; Fouz, B.; Amaro, C.;
Environ Microbiol, 2008; 10(2):328-38
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A common virulence plasmid in biotype 2 Vibrio vulnificus and its dissemination aided by a conjugal plasmid.
Lee, C.T.; Amaro, C.; Wu, K.M.; Valiente, E.; Chang, Y.F.; Tsai, S.F.; Chang, C.H.; Hor, L.I.;
J Bacteriol, 2008; 190(5):1638-48
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Vibrio vulnificus biotype 2 serovar E gne but not galE is essential for lipopolysaccharide biosynthesis and virulence.
Valiente, E.; Jiménez, N.; Merino, S.; Tomás, J.M.; Amaro, C.;
Infect Immun, 2008; 76(4):1628-38
- → View all Dr Esmeralda Valiente's publications
