Dr Richard Stabler PhD
- Richard Stabler's Contacts
- Room 383
- Keppel Street
- WC1E 7HT
- T: 44 207 927 2824
- F: 44 207 637 4314
PhD thesis - Characterisation of a novel pore-forming cytolysin from Mycobacterium tuberculosis and other bacterial patghogens.
I undertook my Ph.D. while working as a research assistant at St Bartholomews Hospital and then LSHTM. After completing the Ph.D. I took a post-doc position at the Bacterial Microarray Group at St. Georges Hospital (BuG@S). I was involved in design, construction, experimental design, application and data analysis on several bacterial projects.
I returned to LSHTM for my second Ph.D position that was primarily to design a microarray that could be used to monitor gene flux of virulence factors. The Active Surveillance of Pathogens (ASP) microarray has been successfully produced and has been used to identify novel virulence determinants in Shigella sonnei and Chromobacterium violaceum.
Course Director for the MSc Medicial Microbiology
Module Organiser for Core Bacteriology and Clinical Bacteriology
Lecturer on the MSc Medicial Microbiology
Lecturer on the MSc Molecular Biology of Infectious Diseases
Lecturer on the MSc Control of Infectious Diseases
Research interests include
i) Clostridium difficile: molecular epidemiology and emergence of hypervirulent isolates.
ii) Methicillin resistant Staphylococcus areus: molecular epidemiology and drug resistance
iii) Campylobacter jejuni: molecular epidemiology and identification of source specific markers.
iv) Escherichia coli K1: Analysis of interaction with and role of gut flora in disease process.
v) Development of drug resistance in Acinetobacter baumannii
vi) Development of drug resistance in Neisseria gonorrhoea
- Genetic epidemiology
- Molecular biology
- Molecular epidemiology
Disease and Health Conditions
- Diarrhoeal diseases
- Infectious disease
- East Asia & Pacific (all income levels)
- Euro area
- Latin America & Caribbean (all income levels)
- North America
- United Kingdom
- United States
- Antimicrobial Resistance
- Bacterial Infections
- Bacterial Pathogenesis
The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications.
Thi Khanh Nhu, N. ; Riordan, D.W. ; Do Hoang Nhu, T. ; Thanh, D.P. ; Thwaites, G. ; Huong Lan, N.P. ; Wren, B.W. ; Baker, S. ; Stabler, R.A. ;
Sci Rep, 2016; 6:28291
The Genotoxin Colibactin is a Determinant of Virulence in Escherichia coli K1 Experimental Neonatal Systemic Infection.
McCarthy, A.J. ; Martin, P. ; Cloup, E. ; Stabler, R. ; Oswald, E. ; Taylor, P.W. ;
Infect Immun, 2015;
Genomic epidemiology of a protracted hospital outbreak caused by a toxin A negative, Clostridium difficile sublineage PCR Ribotype 017 strain in London, England.
Cairns, M.D.; Preston, M.D.; Lawley, T.D.; Clark, T.G.; Stabler, R.A.; Wren, B.W.;
J Clin Microbiol, 2015; 53(10):3141-7
Clonal variation in high- and low-level phenotypic and genotypic mupirocin resistance of MRSA isolates in south-east London.
Hughes, J.; Stabler, R.; Gaunt, M.; Karadag, T.; Desai, N.; Betley, J.; Ioannou, A.; Aryee, A.; Hearn, P.; Marbach, H.; Patel, A.; Otter, J.A.; Edgeworth, J.D.; Tosas Auguet, O.;
J Antimicrob Chemother, 2015; 70(12):3191-9
Staphylococcal Phenotypes Induced by Naturally Occurring and Synthetic Membrane-Interactive Polyphenolic β-Lactam Resistance Modifiers.
Palacios, L. ; Rosado, H. ; Micol, V. ; Rosato, A.E. ; Bernal, P. ; Arroyo, R. ; Grounds, H. ; Anderson, J.C. ; Stabler, R.A. ; Taylor, P.W. ;
PLoS One, 2014; 9(4):e93830
Draft Genome Sequences of Pseudomonas fluorescens BS2 and Pusillimonas noertemannii BS8, Soil Bacteria That Cooperate To Degrade the Poly-γ-d-Glutamic Acid Anthrax Capsule.
Stabler, R.A. ; Negus, D. ; Pain, A. ; Taylor, P.W. ;
Genome Announc, 2013; 1(1)
Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli.
Birchenough, G.M.; Johansson, M.E.; Stabler, R.A.; Dalgakiran, F.; Hansson, G.C.; Wren, B.W.; Luzio, J.P.; Taylor, P.W.;
Infect Immun, 2013; 81(9):3264-75
Macro and Micro Diversity of Clostridium difficile Isolates from Diverse Sources and Geographical Locations
Stabler, R.A.; Dawson, L.F.; Valiente, E.; Cairns, M.D.; Martin, M.J.; Donahue, E.H.; Riley, T.V.; Songer, J.G.; Kuijper, E.J.; Dingle, K.E.; Wren, B.W.;
PLoS One, 2012; 7(3):e31559
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