Liam Smeeth MBChB FRCGP FFPH MSc PhD
Head of the Department of Non-Communicable Disease Epidemiology
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: 020 7927 2296
- F: 020 7580 6897
I trained in medicine and continue to do clinical work as a general practitioner in north London. I joined LSHTM in 1999 and hold a Wellcome Trust senior research fellowship in clinical science. I am Deputy Director of the UCL Partners MRC Centre for Health Service and Academic Partnership in Translational eHealth Research. As well as academic and clinical work I am involved in a range of activities for the National Institute of Health and Clinical Excellence (NICE) and the UK National Health Service more widely. I am vice-chair of the national primary care Quality and Outcomes Framework Advisory Committee. I was appointed as a National Institute for Health Research Senior Investigator in 2011.
Affiliation
Teaching
I am involved in wide range of teaching activities and was previously course director of the MSc epidemiology and then chair of the exam board.
Research
My major interests are in disease aetiology and drug treatments. Two key elements of this work are the use of clinical data derived from primary care for epidemiological research, and utilising genetic research to inform our knowledge of the underlying causes of disease. I also have an interest in non-communicable disease epidemiology in low-income countries, with a particular focus on cardiovascular disease. Examples of recently completed projects include studies establishing that acute infection could trigger both arterial and venous vascular events and work on environmental triggers of myocardial infarction. I have an on-going interest in pharmacoepidemiology, particularly around cardiovascular drugs. For example, we recently demonstrated an increased risk of stroke associated with exposure to anti-psychotic drugs. Other interests include intervention trials, systematic reviews and health inequalities.
Research areas
- Clinical databases
- Primary care
- Randomised controlled trials
- Systematic reviews
Disciplines
- Epidemiology
- Genetic epidemiology
- Medicine
- Pharmacoepidemiology
Disease and Health Conditions
- Cardiovascular disease
- Eye diseases
Regions
- Sub-Saharan Africa (all income levels)
- World
Countries
- Ghana
- India
- Peru
- Uganda
- United Kingdom
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Selected publications
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Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study.
Sundaresan, P. ; Vashist, P. ; Ravindran, R.D. ; Shanker, A. ; Nitsch, D. ; Nonyane, B.A. ; Smeeth, L. ; Chakravarthy, U. ; Fletcher, A.E. ;
Invest Ophthalmol Vis Sci, 2012;
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Heat and risk of myocardial infarction: hourly level case-crossover analysis of MINAP database.
Bhaskaran, K. ; Armstrong, B. ; Hajat, S. ; Haines, A. ; Wilkinson, P. ; Smeeth, L. ;
BMJ, 2012; 345:e8050
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Validation and validity of diagnoses in the General Practice Research Database: a systematic review.
Herrett, E.; Thomas, S.L.; Schoonen, W.M.; Smeeth, L.; Hall, A.J.;
Br J Clin Pharmacol, 2010; 69(1):4-14
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Invasive dental treatment and risk for vascular events: a self-controlled case series.
Minassian, C.; D'Aiuto, F.; Hingorani, A.D.; Smeeth, L.;
Ann Intern Med, 2010; 153(8):499-506
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Influenza as a trigger for acute myocardial infarction or death from cardiovascular disease: a systematic review.
Warren-Gash, C.; Smeeth, L.; Hayward, A.C.;
Lancet Infect Dis, 2009; 9(10):601-10
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Risk of deep vein thrombosis and pulmonary embolism after acute infection in a community setting.
Smeeth, L.; Cook, C.; Thomas, S.; Hall, A.J.; Hubbard, R.; Vallance, P.;
Lancet, 2006; 367(9516):1075-9
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MMR vaccination and pervasive developmental disorders: a case-control study.
Smeeth, L.; Cook, C.; Fombonne, E.; Heavey, L.; Rodrigues, L.C.; Smith, P.G.; Hall, A.J.;
Lancet, 2004; 364(9438):963-9
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Risk of Myocardial Infarction and Stroke after Acute Infection or Vaccination.
Smeeth, L.; Thomas, S.L.; Hall, A.J.; Hubbard, R.; Farrington, P.; Vallance, P.;
N Engl J Med, 2004; 351(25):2611-2618
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