Dr Mark Rowland MSc PhD
- 411
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: 020 7299 4719
Mark Rowland is Head of the Department of Disease Control and Deputy Director of the Malaria Centre. He is a medical entomologist working on the development and evaluation of new methods of malaria vector control.
Mark is Coordinator of PAMVERC, the Pan-African Vector Research Consortium, which is an alliance of field sites, laboratories and research institutions in N Tanzania (Muheza, Moshi, Muleba) and Benin for trialling of new vector control tools to improve malaria transmission control and overcome insecticide resistance.
He has specialist interest in malaria and vector borne disease control in countries affected by crisis and conflict. From 1991 to 1998 he managed the malaria and leishmaniasis control programme of HealthNet-TPO, Medecins sans Frontières and UNHCR in the Afghan refugee camps of Pakistan and in Afghanistan itself. Since returning to LSHTM in 1999 Mark has maintained and built research links with health NGOs working in Afghanistan, Pakistan and Africa.
During the last decade Mark has worked with DFID funded research consortia on integrated malaria control in complex emergencies (epidemiology, medical entomology and malaria chemotherapy) and with the Innovative Vector Control Consortium and private sector manufacturers on vector control product development. He has worked with the WHO Pesticide Evaluation Scheme for over 15 years on the evaluation of mosquito control products.
Affiliation
Teaching
Mark is the Exam Board Chair for the MSc Biology and Control of Disease Vectors. He organises the study module on Vector Biology and Vector Parasite Interactions. He tutors on various MSc courses (BCDV, Medical Parasitology, Control of Infectious Diseases), teaches on various modules (Core Entomology and Parasitology, Integrated Vector Management, and Malaria Epidemiology and Control) and field courses. He supervises PhD students in Tanzania, Benin, Afghanistan and UK.
Research
Research projects in 4 areas:
1. Malaria transmission control:
· A village randomised trial to investigate the impact of indoor residual spraying on malaria transmission in Tanzania and whether universal coverage of long lasting nets can be phased in to sustain control (supported by USAID and President Malaria Initiative).
· A village randomised trial in Tanzania to investigate whether pyrethroid treated blankets/sheets will protect against malaria in a situation analogous to a humanitarian crisis (supported by Sumitomo Corporation).
2. Development of new vector control tools:
Development of cost-effective products that provide longer control and will overcome pyrethroid resistance. These include long-lasting indoor residual spray formulations and combination long-lasting nets. Projects are supported through the Innovative Vector Control Consortium (IVCC), a Gates funded product-development-partnership with agrochemical and textile industry, implemented through PAMVERC in Tanzania and Benin.
Trials of combination products to improve vector control and manage resistance in Africa (AvecNet).
3. Evaluation of new vector control tools:
· Evaluation of new vector control products (LLINs and combination nets) on behalf of the WHO Pesticide Evaluation Scheme (WHOPES). Phase II trials of efficacy and wash resistance in experimental huts, Phase III trials of LLIN effectiveness and durability are evaluated in household randomised trials.
· Comparative studies with prototype or commercial products in laboratory, huts or village trials sponsored by manufacturing industry.
4. Targeting of Rapid Diagnostic Tests (RDT) and Artemesinin Combination Therapy (ACT) for improved management of falciparum and vivax malaria in Afghanistan. A multidisciplinary project funded by the ACT Consortium implemented through the several international and local health care NGOs operating in northern and eastern Afghanistan.
Research areas
- Clinical trials
- Conflict
- Drug resistance
- Insects
- Public health
Disciplines
- Epidemiology
- Vector biology
Disease and Health Conditions
- Infectious disease
- Leishmaniasis
- Malaria
Other interests
- ACT
- Health In Fragile Countries
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Selected publications
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Control of pyrethroid and DDT-resistant Anopheles gambiae by application of indoor residual spraying or mosquito nets treated with a long-lasting organophosphate insecticide, chlorpyrifos-methyl.
N'guessan, R.; Boko, P.; Odjo, A.; Chabi, J.; Akogbeto, M.; Rowland, M.;
Malar J, 2010; 9(1):44
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The Impact of Phenotypic and Genotypic G6PD Deficiency on Risk of Plasmodium vivax Infection: A Case-Control Study amongst Afghan Refugees in Pakistan.
Leslie, T.; Brice?o, M.; Mayan, I.; Mohammed, N.; Klinkenberg, E.; Sibley, C.H.; Whitty, C.J.; Rowland, M.;
PLoS Med, 2010; 7(5):e1000283
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A randomised trial of an eight-week, once weekly primaquine regimen to prevent relapse of plasmodium vivax in Northwest Frontier Province, Pakistan.
Leslie, T.; Mayan, I.; Mohammed, N.; Erasmus, P.; Kolaczinski, J.; Whitty, C.J.; Rowland, M.;
PLoS ONE, 2008; 3(8):e2861
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Reduced efficacy of insecticide-treated nets and indoor residual spraying for malaria control in pyrethroid resistance area, Benin
N'Guessan, R.; Corbel, V.; Akogbeto, M.; Rowland, M.
Emerging Infectious Diseases, 2007; 13(2):199-206
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Insecticide-treated nets.
Hill, J.; Lines, J.; Rowland, M.;
Adv Parasitol, 2006; 61:77-128
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Malaria control in Afghanistan: progress and challenges.
Kolaczinski, J.; Graham, K.; Fahim, A.; Brooker, S.; Rowland, M.;
Lancet, 2005; 365(9469):1506-12
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DEET mosquito repellent provides personal protection against malaria: a household randomized trial in an Afghan refugee camp in Pakistan
Rowland, M.; Downey, G.; Rab, A.; Freeman, T.; Mohammad, N.; Rehman, H.; Durrani, N.; Reyburn, H.; Curtis, C.; Lines, J.; Fayaz, M.
Tropical Medicine & International Health, 2004; 9(3):335-42
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Control of malaria in Pakistan by applying deltamethrin insecticide to cattle: a community-randomised trial
Rowland, M.; Durrani, N.; Kenward, M.; Mohammed, N.; Urahman, H.; Hewitt, S.
Lancet, 2001; 357(9271):1837-1841
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