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Mr Alexander Perkins

Research Fellow

London School of Hygiene & Tropical Medicine
Keppel Street
London
WC1E 7HT
United Kingdom

Alexander has worked at the London School of Hygiene & Tropical Medicine since 2016, and has been involved with clinical trials in Canada, the UK, Europe and sub-Saharan Africa since 2014. His research is mainly in cardiovascular medicine, specifically in emergency and low-resource settings. Alexander is the Deputy Director of the Centre for Global Chronic Conditions, and runs a cardiovascular research interest group. Prior to joining the LSHTM, he worked at the University of British Columbia in Vancouver, Canada studying muscle cell biology and genetics in fruit flies.

Affiliations

Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Centres

Centre for Global Chronic Conditions

Teaching

Alexander's teaching focusses on clinical trials and epidemiology. He teaches on both distance learning and in person modules as well as short courses. He is the Deputy Module Organiser for CTM210, the final module for the distance learning MSc in Clinical Trials. Alexander has been involved with the Clinical Trials short course since 2018. In 2023, he worked with colleagues to run the short course at the MRC Unit in the Gambia for the first time.

Alexander completed the Post-Graduate Certificate in Teaching and Learning (PGCILT) in 2022 and am a AdvanceHE Fellow (FHEA).

Research

Research Area
Clinical trials
Epidemiology
Field epidemiology
Research ethics
Randomised controlled trials
Disease and Health Conditions
Heart disease
Hypertension
Cardiovascular diseases
Country
United Kingdom
Kenya
Gambia
Region
European Union
Sub-Saharan Africa (all income levels)
North America

Selected Publications

Determining the optimal diagnostic and risk stratification approaches for people with hypertension in two rural populations in Kenya and The Gambia: a study protocol for IHCoR-Africa Work Package 2
PERKINS, A; Awori, JO; JOBE, M; Lucinde, R; Siemonsma, M; Oyando, R; Leon, D; Herrett, E; Prentice, A; Shah, AS V; Perel, P; Etyang, A; The IHCoR-Africa Collaborators,;
2023
NIHR Open Res
Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial.
Patterson, T; Perkins, GD; PERKINS, A; CLAYTON, T; EVANS, R; DODD, M; ROBERTSON, S; Wilson, K; Mellett-Smith, A; Fothergill, RT; McCrone, P; Dalby, M; MacCarthy, P; Firoozi, S; Malik, I; Rakhit, R; Jain, A; Nolan, JP; Redwood, SR; ARREST trial collaborators,;
2023
Lancet (London, England)
Complex and alternate consent pathways in clinical trials: methodological and ethical challenges encountered by underserved groups and a call to action.
Russell, AM; Shepherd, V; Woolfall, K; Young, B; Gillies, K; Volkmer, A; Jayes, M; Huxtable, R; PERKINS, A; Noor, NM; Nickolls, B; Wade, J;
2023
Trials
Routine cerebral embolic protection in transcatheter aortic valve implantation: rationale and design of the randomised British Heart Foundation PROTECT-TAVI trial.
Kharbanda, RK; PERKINS, AD; Kennedy, J; Banning, AP; Baumbach, A; Blackman, DJ; DODD, M; EVANS, R; Hildick-Smith, D; JAMAL, Z; Ludman, P; Palmer, S; Stables, R; CLAYTON, T;
2023
EuroIntervention
Statins do not commonly cause muscle pain and stiffness.
Saul, H; Gursul, D; Cassidy, S; SMEETH, L; PERKINS, A;
2021
BMJ-BRITISH MEDICAL JOURNAL
StatinWISE study data
SMEETH, L; PERKINS, A; WILLIAMSON, E;
2021
London School of Hygiene & Tropical Medicine
Effect of remote ischaemic conditioning on infarct size and remodelling in ST-segment elevation myocardial infarction patients: the CONDI-2/ERIC-PPCI CMR substudy.
Francis, R; Chong, J; Ramlall, M; Bucciarelli-Ducci, C; CLAYTON, T; DODD, M; Engstrøm, T; EVANS, R; Ferreira, VM; Fontana, M; Greenwood, JP; Kharbanda, RK; Kim, WY; Kotecha, T; Lønborg, JT; Mathur, A; Møller, UK; Moon, J; PERKINS, A; Rakhit, RD; Yellon, DM; Bøtker, HE; Bulluck, H; Hausenloy, DJ;
2021
Basic Research in Cardiology
Translation of experimental cardioprotective capability of P2Y12 inhibitors into clinical outcome in patients with ST-elevation myocardial infarction.
Hjortbak, MV; Olesen, KK W; Seefeldt, JM; Lassen, TR; Jensen, RV; PERKINS, A; DODD, M; CLAYTON, T; Yellon, D; Hausenloy, DJ; Bøtker, HE; CONDI-2/ERIC-PPCI investigators,;
2021
Basic research in cardiology
Patient and public involvement prior to trial initiation: lessons learnt for rapid partnership in the COVID-19 era.
JAMAL, Z; PERKINS, A; Allen, C; Research Advisory Group,; EVANS, R; STURGESS, J; SNOWDON, C; CLAYTON, T; ELBOURNE, D;
2021
Research involvement and engagement
The effect of statins on muscle symptoms in primary care: the StatinWISE series of 200 N-of-1 RCTs.
HERRETT, E; WILLIAMSON, E; Brack, K; PERKINS, A; Thayne, A; SHAKUR-STILL, H; ROBERTS, I; Prowse, D; BEAUMONT, D; JAMAL, Z; GOLDACRE, B; Van Staa, T; MacDonald, TM; Armitage, J; Moore, M; Hoffman, M; SMEETH, L;
2021
Health technology assessment (Winchester, England)
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