Dorothea Nitsch MD MSc
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- LSHTM
- Keppel Street
- London
- WC1E 7HT
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Dorothea graduated in Medicine at the University of Basel (Switzerland) and did her Doctoral Thesis there at the Biocenter. She worked several years in Internal Medicine and Renal Medicine in Switzerland up to specialist level. She obtained an MSc in Medical Statistics at the London School of Hygiene and Tropical Medicine in 2003 and joined directly afterwards.
Affiliation
Teaching
She is the course co-director of the MSc in Epidemiology and helps tutoring in the MSc Medical Statistics.
Research
Dorothea's research focuses on risk factors and outcomes of chronic kidney disease.
She has an interest in statistical issues in genetic and life-course epidemiology of chronic kidney disease. In collaboration with the MRC 1946 cohort study (principal investigator: Professor Diana Kuh) she is currently exploring whether there are important life-course risk factors for chronic kidney disease in the UK general population. In collaboration with Professor Astrid Fletcher (LSHTM) and Professor Paul Roderick (University of Southampton) she investigates outcomes of older people with chronic kidney disease using data from the MRC at Older Age study. The study also contributes data to the Chronic Kidney disease Prognosis Consortium (CKD PC) in which Dorothea is involved in analyses comparing outcomes of men and women who have CKD. Dorothea collaborates with clinicians who are based at the UCL centre of Nephrology at the Royal Free Hospital, and with the UK Renal Registry to investigate outcomes of people on dialysis and transplantion.
Research areas
- Ageing
Disciplines
- Epidemiology
- Genetic epidemiology
- Life-course epidemiology
- Medicine
- Statistics
Disease and Health Conditions
- Cardiovascular disease
- Chronic disease
- Eye diseases
- Kidney disease
Regions
- Euro area
- North America
- South Asia
- Sub-Saharan Africa (all income levels)
Other interests
- Causal Inference
- Chronic kidney disease
- Epidemiological Methods
- MARCH
- clinical epidemiology
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Selected publications
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Blood Pressure and Mortality Risk on Peritoneal Dialysis
Udayaraj, U.P.; Steenkamp, R.; Caskey, F.J.; Rogers, C.; Nitsch, D.; Ansell, D.; Tomson, C.R.V.
American Journal of Kidney Diseases, 2009; 53(1):70-78
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A structured approach to modelling the effects of binary exposure variables over the life course
Mishra, G.; Nitsch, D.; Black, S.; de Stavola, B.; Kuh, D.; Hardy, R.
International Journal of Epidemiology, 2009; 38(2):528-537
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Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus.
Hunnangkul, S.; Nitsch, D.; Rhodes, B.; Chadha, S.; Roberton, C.A.; Pessôa-Lopes, P.; Norsworthy, P.J.; Fernando, M.M.; Charles, P.; Mackworth-Young, C.; Isenberg, D.A.; Whittaker, J.C.; Vyse, T.J.;
Arthritis Rheum, 2008; 58(4):1116-1124
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Age-Related Macular Degeneration and Complement Activation-Related Diseases A Population-Based Case-Control Study.
Nitsch, D.; Douglas, I.; Smeeth, L.; Fletcher, A.;
Ophthalmology, 2008; 115(11):1904-10
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Prevalence of renal impairment and its association with cardiovascular risk factors in a general population: results of the Swiss SAPALDIA study.
Nitsch, D.; Dietrich, D.F.; von Eckardstein, A.; Gaspoz, J.M.; Downs, S.H.; Leuenberger, P.; Tschopp, J.M.; Brändli, O.; Keller, R.; Gerbase, M.W.; Probst-Hensch, N.M.; Stutz, E.Z.; Ackermann-Liebrich, U.;
Nephrol Dial Transplant, 2006; 21(4):935-44
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Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials.
Nitsch, D.; Molokhia, M.; Smeeth, L.; De Stavola, B.L.; Whittaker, J.C.; Leon, D.A.;
Am J Epidemiol, 2006; 163(5):397-403
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Renal function as a predictor of outcome in a broad spectrum of patients with heart failure
Hillege, H. L.; Nitsch, D.; Pfeffer, M. A.; Swedberg, K.; McMurray, J. J. V.; Yusuf, S.; Granger, C. B.; Michelson, E. L.; Ostergren, J.; Cornel, J. H.; de Zeeuw, D.; Pocock, S.; van Veldhuisen, D. J.
Circulation, 2006; 113(5):671-678
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Linkage bias in estimating the association between childhood exposures and propensity to become a mother: an example of simple sensitivity analyses
Nitsch, D.; De Stavola, B. L.; Morton, S. M. B.; Leon, D. A.
Journal of the Royal Statistical Society Series a-Statistics in Society, 2006; 169:493-505
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