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Miss Victoria Miari

Principal Scientific Officer

United Kingdom

Trained and HCPC registered Clinical Scientist in Microbiology, with a specialist interest in Sexually Transmitted Infections. Has been involved in various research studies including HSV, syphilis and gonorrhoea. A particular interest is antimicrobial resistance in STIs and specifically Neisseria gonorrhoeae. Received B.Sc. in Infectious Diseases from the University of East London and subsequently gained an M.Sc. in Clinical Microbiology by Queen Mary University of London and Pg.Dip. in Sexual Health by Glasgow Caledonian University. Was accepted in the competitive clinical scientist training programme with the British National Health Service and as part of this, sat the FRCPath Part 1 examination in Clinical Microbiology.

Victoria shortlists and assesses for the NHS Scientist Training Programme and part of the London Training Consortium for STP Trainees.

Is currently a member of the Association for Clinical Biochemistry and Laboratory Medicine and has held the following roles: 1) Deputy Director for Scientific Affairs, Scientific & Clinical Practice Committee, 2) Lead for Scientific & Clinical Practice, Microbiology Committee. Is a member of the Standards for microbiological Investigation Bacteriology working group and member of the Bacteriology Interest group of the British ssociation for Sexual Health & HIV.

Affiliations

Faculty of Infectious and Tropical Diseases

Centres

Antimicrobial Resistance Centre

Teaching

Teaching

MSc Programmes:

Medical Microbiology

Control of Infectious Diseases

MSc Modules:

Core Bacteriology & Virology

Clinical Bacteriology 1 & 2 (Deputy MO)

Clinical Virology (Deputy MO)

Mycology (Deputy DMO)

Antimicrobial Chemotherapy

She leads the Core Bacteriology module practical teaching for the MSc in Medical Microbiology and supports practical classes for clinical bacteriology, core virology, clinical virology and mycology modules. She also the deputy module organiser for the Clinical Virology, Clinical Bacteriology 1 & 2 and Mycology.

She also delivers lectures in the Core Bacteriology and Clinical Bacteriology modules. She regularly supervises MSc project students.

2013-2014: Multi-site Neisseria gonorrhoeae infection and antimicrobial resistance

2014-2015: Optimisation of broth culture for Neisseria gonorrhoeae and gene transfer from commensal Neisserias

2016-2017: Understanding the mechanism of resistance for the novel antimicrobial closthioamide in Neisseria gonorrhoeae

2018-2019: Antimicrobial susceptibility of N. gonorrhoeae strains to chlorhexidine by agar dilution and microbroth dilution method

2018-2019: Carriage and characterisation of commensal Neisseria species in the human pharynx

2019-2020: Literature Review of Viability PCR within Clinical Microbiology

2019-2020: Systematic Review of gonococcal post-cephalospirin treatment failures

2021-2022: Induction of chlorhexidine resistance in susceptible Neisseria gonorrhoeae strains

Research

Research interests: Clinical diagnostics, Antimicrobial resistance, Sexually Transmitted Infections, Neisseria gonorrhoeae, Pharyngeal gonorrhoea, AMR surveillance, Health Services Research.

Victoria’s research focuses on antimicrobial resistant gonorrhoea and how pharyngeal infection facilitates development and transmission of AMR. Specifically she is interested in the role of commensal species in the genetic transfer of AMR genes, as well as the evaluation novel treatments for gonorrhoea such as topical antiseptics.

She is now evaluating the in vitro efficacy of chlorhexidine against N. gonorrhoeae with the view to implement chlorhexidine containing solutions as gonococcal treatment, thereby improving antimicrobial stewardship.

As part of her expertise in diagnostics, antimicrobial susceptibility testing and public health, she is also interested in multi-site gonorrhoea infection and how that impacts on the above areas.

Research Area
Microbiology
Clinical research
AMR (Antimicrobial resistance)
Antimicrobial agents
Sexual health
Diagnostics
Laboratory diagnosis
Development studies
Clinical trials
Disease and Health Conditions
Gonorrhoea
Sexually transmitted infections
Country
United Kingdom
Region
Euro area

Selected Publications

Ethnically diverse urban transmission networks of Neisseria gonorrhoeae without evidence of HIV serosorting.
Dave, J; Paul, J; Pasvol, TJ; Williams, A; Warburton, F; Cole, K; MIARI, VF; STABLER, R; Eyre, DW;
2019
Sexually transmitted infections
In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae.
MIARI, VF; Solanki, P; Hleba, Y; STABLER, RA; Heap, JT;
2017
Antimicrobial agents and chemotherapy
Is there a role for topical antiseptics in the treatment of gonorrhoea?
MIARI, VF; Ison, CA;
2016
Sexually transmitted infections
Accurate detection of Neisseria gonorrhoeae ciprofloxacin susceptibility directly from genital and extragenital clinical samples: towards genotype-guided antimicrobial therapy.
Pond, MJ; HALL, CL; MIARI, VF; Cole, M; Laing, KG; Jagatia, H; HARDING-ESCH, E; Monahan, IM; Planche, T; Hinds, J; Ison, CA; Chisholm, S; Butcher, PD; Sadiq, ST;
2016
The Journal of antimicrobial chemotherapy
Evaluation of non-extracted genital swabs for real-time HSV PCR.
MIARI, VF; Wall, GR; Clark, DA;
2014
Journal of medical virology
Is gonorrhea becoming untreatable?
Blomquist, PB; MIARI, VF; Biddulph, JP; Charalambous, BM;
2014
Future microbiology
Minimum inhibitory concentrations of extended spectrum cephalosporins: A systematic review and meta-analysis of Neisseria gonorrhoeae treatment failure
MIARI, VF; Mosoff, JM; CHICO, RM;
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