Dr Ruth Mcnerney PhD
- Ruth Mcnerney's Contacts
- Room 360
- Keppel Street
- WC1E 7HT
- T: +44 (0) 20 7927 2346
Ruth Mcnerney's Background
Ruth McNerney is an expert on tuberculosis. She is a member of the STOP TB Working Group on New Diagnostics and is a Director of TBAlert, the UK's TB charity that works in the UK, Africa and India. She is currently working on projects to improve access to affordable diagnostics in developing countries. Her previous research has included the development, adaptation and evaluation of tools for the control of tuberculosis. This includes diagnosis, detection of drug resistance, molecular epidemiology and whole genome sequencing. She also has an interest in transmission of the disease. She is experienced in molecular techniques, immunoassay, and previously developed a simple, rapid, low-cost test for drug susceptibility using bacteriophages. She has a strong interest in POC tests and is currently collaborating on a project to transfer a new blood based test for active TB to a detection platform for use at the point of care. She has also developed patient based educational materials to assist diagnosis. She receives no financial support from LSHTM.
Ruth Mcnerney's Affiliation
Ruth Mcnerney's Teaching
Ruth McNerney teaches students studying control of infectious diseases, molecular biology of infectious diseases and chemotherapy and anti-microbial resistance.
Ruth Mcnerney's Research
Project: Improving Regulatory Oversight Of In-Vitro Diagnostics In The Developing World: Affordable access to in-vitro diagnostics through regulatory harmonization approaches. Funding from Grand Challenges Canada
Project: Improving access to medical products in developing countries through building capacity for local production and related technology transfer. Funding from WHO, through a grant from the European Union.
Project: Research to create point-of-care TB diagnostic prototype from ProteinLogic unique TB biomarker signature and Microtest Matrices novel rapid diagnostic platform Funding: Technology Strategy Board
- Drug resistance
- Molecular epidemiology
- Operational research
Disease and Health Conditions
- Infectious disease
- MDR TB
Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing.
Clark, T.G. ; Mallard, K. ; Coll, F. ; Preston, M. ; Assefa, S. ; Harris, D. ; Ogwang, S. ; Mumbowa, F. ; Kirenga, B. ; O'Sullivan, D.M. ; Okwera, A. ; Eisenach, K.D. ; Joloba, M. ; Bentley, S.D. ; Ellner, J.J. ; Parkhill, J. ; Jones-López, E.C. ; McNerney, R. ;
PLoS One, 2013; 8(12):e83012
Production of volatile organic compounds by mycobacteria.
McNerney, R. ; Mallard, K. ; Okolo, P.I. ; Turner, C. ;
FEMS Microbiol Lett, 2012;
Microscopy compared to culture for the diagnosis of tuberculosis in induced sputum samples: a systematic review.
Hepple, P. ; Ford, N. ; McNerney, R. ;
Int J Tuberc Lung Dis, 2012; 16(5):579-88
Tuberculosis Diagnostics and Biomarkers: Needs, Challenges, Recent Advances, and Opportunities.
McNerney, R. ; Maeurer, M. ; Abubakar, I. ; Marais, B. ; McHugh, T.D. ; Ford, N. ; Weyer, K. ; Lawn, S. ; Grobusch, M.P. ; Memish, Z. ; Squire, S.B. ; Pantaleo, G. ; Chakaya, J. ; Casenghi, M. ; Migliori, G.B. ; Mwaba, P. ; Zijenah, L. ; Hoelscher, M. ; Cox, H. ; Swaminathan, S. ; Kim, P. ; Schito, M. ; Harari, A. ; Bates, M. ; Schwank, S. ; O'Grady, J. ; Pletschette, M. ; Ditui, L. ; Atun, R. ; Zumla, A. ;
J Infect Dis, 2012;
Towards a point-of-care test for active tuberculosis: obstacles and opportunities.
McNerney, R. ; Daley, P. ;
Nat Rev Microbiol, 2011; 9(3):204-13
Effectiveness of the Standard WHO Recommended Retreatment Regimen (Category II) for Tuberculosis in Kampala, Uganda: A Prospective Cohort Study.
Jones-López, E.C. ; Ayakaka, I. ; Levin, J. ; Reilly, N. ; Mumbowa, F. ; Dryden-Peterson, S. ; Nyakoojo, G. ; Fennelly, K. ; Temple, B. ; Nakubulwa, S. ; Joloba, M.L. ; Okwera, A. ; Eisenach, K.D. ; McNerney, R. ; Elliott, A.M. ; Ellner, J.J. ; Smith, P.G. ; Mugerwa, R.D. ;
PLoS Med, 2011; 8(3):e1000427
Screening of immigrants in the UK for latent tuberculosis.
McNerney, R. ; Ferrara, G. ; O'Grady, J. ; Maeurer, M. ; Zumla, A. ;
Expert Rev Respir Med, 2011; 5(4):483-6
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