David Leon BA (Hons) PhD

- Room 258b
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: +44 (0)20 7927 2252
- F: +44 (0)20 7580 6897
I went to to Cambridge university in 1971 to study natural sciences, with a passion for biochemistry. However, in a moment of idealism, I changed to philosophy and sociology, graduating in 1974. In 1978 I returned to science in my first job in epidemiology, and in 1985 I joined LSHTM as a lecturer in epidemiology. In 1991 I obtained a PhD in epidemiology from the University of London and in 2001 I was awarded an honorary doctorate in the faculty of medicine from the University of Uppsala, Sweden. I am a visiting professor at the Universities of Stockholm, Bristol and Glasgow, and in 2008 I was made an Honorary Academician of the Izhevsk State Medical Academy in Russia. Since October 2008 I have been deputy chair of the MRC's Population and System Medicine Board.
Affiliation
Teaching
I currently teach on a wide range of MSc courses at LSHTM including the introductory course on epidemiology. I also co-organise the Epidemiology of Non-communicable Diseases study unit in Term 2. This study unit aims to convey the growing importance of a wide range of non-communicable diseases throughout the world including cardiovascular disease, diabetes, cancer and mental health and injuries and violence.
Research
Over the past 15 years I have developed two main strands to my research. The first has involved setting up studies on the fetal and developmental origins of adult disease. With MRC funding I set up a number of studies with Swedish colleagues in Uppsala (the Uppsala Birth Cohort Study and the Uppsala Family Study) that have made contributions to the field particularly with respect to the association of foetal growth with blood pressure and the risk of cardiovascular disease and cancer. I have also worked with colleagues in the UK to create a research platform for life-course epidemiology based on a cohort of 12 thousand men and women born in Aberdeen, Scotland in the early 1950s : The Aberdeen Children of the 1950s study.
The second strand has involved studying the health of populations of the former communist countries of Eastern Europe. This has increasingly focussed upon the role of alcohol as a key (proximal) factor in explaining the huge fluctuations that here have been in working age mortality in Russia since the mid-1980s. Collaborating with colleagues in Russia, Germany, Estonia and the UK we are studying the contribution of hazardous drinking to ill health and mortality. This is funded by a Wellcome Trust research programme (2006-2010) that includes an intervention trial as well as in-depth studies of the dynamics of alcohol drinking among men.
Research areas
- Alcohol
- Behaviour change
- Child health
- Global Health
- International comparisons
- Public health
- Substance abuse
Disciplines
- Epidemiology
- Life-course epidemiology
Disease and Health Conditions
- Addiction
- Cardiovascular disease
- Non-communicable diseases
Regions
- Europe & Central Asia (all income levels)
- European Union
Countries
- Russian Federation
Other interests
- autopsy
- mortality trends
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Selected publications
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Long term trends in longevity of scientific elites: evidence from the British and the Russian academies of sciences
Andreev, E.; Jdanov, D.; Shkolnikov, V.M.; and Leon, D.A.;
Population Studies, In Press;
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Hazardous alcohol consumption is a major factor in male premature mortality in a typical Russian city: prospective cohort study 2003-2009.
Tomkins, S. ; Collier, T. ; Oralov, A. ; Saburova, L. ; McKee, M. ; Shkolnikov, V. ; Kiryanov, N. ; Leon, D.A. ;
PLoS One, 2012; 7(2):e30274
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Trends in European life expectancy: a salutary view.
Leon, D.A. ;
Int J Epidemiol, 2011;
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Alcohol increases circulatory disease mortality in Russia: acute and chronic effects or misattribution of cause?
Leon, D.A.; Shkolnikov, V.M.; McKee, M.; Kiryanov, N.; Andreev, E.;
Int J Epidemiol, 2010; 39(5):1279-90
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The association of childhood intelligence with mortality risk from adolescence to middle age: Findings from the Aberdeen Children of the 1950s cohort study
Leon, D.A.; Lawlor, D.A.; Clark, H.; Batty, G.D.; MacIntyre, S.
Intelligence, 2009; 37(6):520-528
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Availability and Characteristics of Nonbeverage Alcohols Sold in 17 Russian Cities in 2007.
Gil, A.; Polikina, O.; Koroleva, N.; McKee, M.; Tomkins, S.; Leon, D.A.;
Alcohol Clin Exp Res, 2008; 33(1):79-85
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Hazardous alcohol drinking and premature mortality in Russia: a population based case-control study.
Leon, D.A.; Saburova, L.; Tomkins, S.; Andreev, E.; Kiryanov, N.; McKee, M.; Shkolnikov, V.M.;
Lancet, 2007; 369(9578):2001-9
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Liver cirrhosis mortality rates in Britain from 1950 to 2002: an analysis of routine data.
Leon, D.A.; McCambridge, J.;
Lancet, 2006; 367(9504):52-6
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