Dr Natasha Larke BSc MSc DPhil
- Natasha Larke's Contacts
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- WC1E 7HT
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I joined the school in 2006 as an epidemiologist/ medical statistician in the MRC Tropical Epidemiology Group. I began my research career as a basic scientist, completing my PhD in HIV vaccine research at Oxford University with Sir Andrew McMichael. Following my doctoral studies, I retrained in Epidemiology at LSHTM and subsequently joined the school as a member of staff.
I organise and teach on the Cluster Randomised Trials module. I have also taught on several other Epidemiology modules including, Epidemiology and Control of Communicable Diseases (ECCD), Statistical Methods in Epidemiology (SME) and Statistics for Epidemiology and Population Health (STEPH).
My main research interests are in the epidemiology of HIV and STIs in developing countries. I have worked on several observational studies and intervention trials, including studies with the MRC/UVRI Uganda Research Unit on AIDS, the MEMA kwa Vijana trial of educational intervention in young people and the Chilenje Infant Growth, Nutrition and Infection study. I have also worked on a number of systematic reviews including one demonstrating a protective effect of male circumcision on HPV infection.
- Clinical trials
- Sexual health
- Systematic reviews
Disease and Health Conditions
- Infectious disease
- Sexually transmitted infection
- Sub-Saharan Africa (all income levels)
Causes of acute hospitalization in adolescence: burden and spectrum of HIV-related morbidity in a country with an early-onset and severe HIV epidemic: a prospective survey.
Ferrand, R.A.; Bandason, T.; Musvaire, P.; Larke, N.; Nathoo, K.; Mujuru, H.; Ndhlovu, C.E.; Munyati, S.; Cowan, F.M.; Gibb, D.M.; Corbett, E.L.;
PLoS Med, 2010; 7(2):e1000178
Complications of circumcision in male neonates, infants and children: a systematic review.
Weiss, H.A.; Larke, N.; Halperin, D.; Schenker, I.;
BMC Urol, 2010; 10(1):2
Undetectable plasma viral load predicts normal survival in HIV-2-infected people in a West African village
van der Loeff, M.F.S.; Larke, N.; Kaye, S.; Berry, N.; Ariyoshi, K.; Alabi, A.; van Tienen, C.; Leligdowicz, A.; Sarge-Njie, R.; da Silva, Z.; Jaye, A.; Ricard, D.; Vincent, T.; Jones, S.R.; Aaby, P.; Jaffar, S.; Whittle, H.
Retrovirology, 2010; 7
Male circumcision, HIV and sexually transmitted infections: a review.
Br J Nurs, 2010; 19(10):629-34
Impact of the MEMA kwa Vijana Adolescent Sexual and Reproductive Health Interventions on Use of Health Services by Young People in Rural Mwanza, Tanzania: Results of a Cluster Randomized Trial.
Larke, N.; Cleophas-Mazige, B.; Plummer, M.L.; Obasi, A.I.; Rwakatare, M.; Todd, J.; Changalucha, J.; Weiss, H.A.; Hayes, R.J.; Ross, D.A.;
J Adolesc Health, 2010; 47(5):512-22
Design of epidemiological studies measuring genital and plasma HIV-1 outcomes: lessons from a randomised controlled trial.
Larke, N.L.; Weiss, H.A.; Mayaud, P.; Van de Perre, P.; Clayton, T.; Ouedraogo, A.; Nagot, N.;
Trop Med Int Health, 2009; 14(3):267-75
Combined single-clade candidate HIV-1 vaccines induce T cell responses limited by multiple forms of in vivo immune interference.
Larke, N.; Im, E.J.; Wagner, R.; Williamson, C.; Williamson, A.L.; McMichael, A.J.; Hanke, T.;
Eur J Immunol, 2007; 37(2):566-77
Induction of human immunodeficiency virus type 1-specific T cells by a bluetongue virus tubule-vectored vaccine prime-recombinant modified virus Ankara boost regimen.
Larke, N.; Murphy, A.; Wirblich, C.; Teoh, D.; Estcourt, M.J.; McMichael, A.J.; Roy, P.; Hanke, T.;
J Virol, 2005; 79(23):14822-33
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