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Dr Harparkash Kaur

BSc PhD CSci CChem FRSC

Assistant Professor
Pharmacology

 Dr Harparkash Kaur gained both her BSc with honours and PhD in chemistry from the Chelsea College (now Kings College), University of London.

PhD thesis: Free Radical Chemistry: Pericyclic Rearrangements and some new spin traps. 

Elected chartered chemist, fellow of the Royal Society of Chemistry in 1999 (CChem FRSC) and designated a chartered scientist (CSci) in 2005.

Harparkash joined LSHTM in 2001 as staff on the Gates Malaria Partnership and is a founder member of the artemisinin combination therapy consortium. She is the lead investigator of the drug quality project(www.actconsortium.org/drugquality).

Affiliations

Department of Clinical Research
Immunology and Infection Department
Faculty of Infectious and Tropical Diseases
Department of Disease Control

Centres

Malaria Centre
Antimicrobial Resistance Centre

Teaching

  • Academic organiser of the Masters Module "Control and Epidemiology of Malaria".
  • Supervision of MSc projects and practical teaching of chromatographic techniques on Antimicrobial Chemotherapy Study Module.
  • Teaching on both of the above mentioned Study Modules.
  • Supervisor to PhD students.

Research

Harparkash set up the bio analytical laboratory at LSHTM. As an analyst she devised high performance liquid chromatography (HPLC) based methods applicable to varying fields of research such as determining the levels of free radicals in disease state and levels of endogenous antioxidants. Her present research has involved developing / validating HPLC and simple chemical methods to test the quality as well as levels of drugs in patient samples and measuring the levels of insecticids on treated nets and indoor residual spraying that are used as the major mode of intervention in the fight against malaria. The field friendly methods that she has devised for the detection of artemisnin derivatives and for the detection of insecticides have separate granted patents held by the LSHTM. The focus of her work recently been to determine the quality of drugs, levels of antimalarial drugs on filter paper adsorbed blood samples and amounts of insecticides on bed nets from a number of trials ongoing/planned in Sub-Saharan Africa.

Research Area
Pharmacokinetics
Qualitative methods
Vector control
Discipline
Pharmacology
Disease and Health Conditions
Infectious disease
Malaria
Neglected Tropical Diseases (NTDs)
Country
Afghanistan
Ghana
Equatorial Guinea
Cambodia
Nigeria
Rwanda
Tanzania
Region
South Asia
Sub-Saharan Africa (developing only)
Sub-Saharan Africa (all income levels)

Selected Publications

Fake anti-malarials: start with the facts.
Kaur, H. ; Clarke, S. ; Lalani, M. ; Phanouvong, S. ; Guérin, P. ; McLoughlin, A. ; Wilson, B.K. ; Deats, M. ; Plançon, A. ; Hopkins, H. ; Miranda, D. ; Schellenberg, D. ;
Malar J
Degradation of Artemisinin-Based Combination Therapies Under Tropical Conditions.
Hall, Z.; Allan, E.L.; van Schalkwyk, D.A.; van Wyk, A.; Kaur, H.;
Am J Trop Med Hyg
Chemical and Bioassay Techniques to Authenticate Quality of the Anti-Leishmanial Drug Miltefosine.
Kaur, H.; Seifert, K.; Hawkes, G.E.; Coumbarides, G.S.; Alvar, J.; Croft, S.L.;
Am J Trop Med Hyg
Quality of Artemisinin-Containing Antimalarials in Tanzania's Private Sector--Results from a Nationally Representative Outlet Survey.
ACT Consortium Drug Quality Project Team and the IMPACT2 Study Team, . ;
Am J Trop Med Hyg
Quality of artemisinin-based combination formulations for malaria treatment: prevalence and risk factors for poor quality medicines in public facilities and private sector drug outlets in enugu, Nigeria.
Kaur, H. ; Allan, E.L. ; Mamadu, I. ; Hall, Z. ; Ibe, O. ; El Sherbiny, M. ; Wyk, A.v. ; Yeung, S. ; Swamidoss, I. ; Green, M.D. ; Dwivedi, P. ; Culzoni, M.J. ; Clarke, S. ; Schellenberg, D. ; Fernández, F.M. ; Onwujekwe, O. ;
PLoS One
Counterfeit Pharmaceuticals and Methods to Test Them
Kaur, H.
Annual Report of the Government Chief Scientific Adviser 2015: Forensic Science and Beyond: Authenticity, Provenance and Assurance Evidence and Case Studies
COLORIMETRIC ASSAY FOR PYRETHROID INSECTICIDES
Kaur, H; Eggelte, T
UK Intellectual Property Office
ASSAY, KIT AND APPARATUS FOR DETECTION OF ARTEMISININ DERIVATIVES
Kaur, H.; Ioset, J.-R.
UK Intellectual Property Office
See all Dr Harparkash Kaur's Publications