Alison Grant MBBS MSc PhD DTM&H

- Room 301
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: +44 20 7927 2304
- F: +44 20 7636 8739
I trained initially as a physician specialising in infectious and tropical diseases and HIV medicine, and continue to work in HIV medicine in London. I studied epidemiology at LSHTM with particular interests in care for HIV-infected people in developing countries.
Affiliation
Teaching
I teach clinical tropical medicine, epidemiology and HIV/AIDS to wide range of students. From 1999-2003 I was Course Organiser for MSc Tropical Medicine and International Health.
Research
My main research interest is care for people with HIV in developing countries, particularly preventive interventions. Currently major projects include a cluster randomised trial investigating the effect of community-wide TB preventive therapy among gold miners in South Africa, a component of the CREATE consortium, funded by the Bill and Melinda Gates Foundation; evaluation of South African national roll-out of a new test for TB, Xpert MTB/RIF; and a trial of a point-of-care TB test and treat algorithm for people with advanced HIV disease. In collaboration with colleagues in South Africa, I have been involved with the design, implementation and evaluation of an HIV care programme in workplace and community settings.
I supervise research degree students working on second-line antiretroviral therapy in South Africa; the effect of antiretroviral therapy on households in Uganda; missed opportunities in enrolling pregnant women into HIV care programmes in Kenya; and retention in ART programmes in Zimbabwe.
I did field work for my PhD on the clinical epidemiology of HIV disease at Projet RETRO-CI, Abidjan, Côte d'Ivoire, where I was also involved in a study of the effect of cotrimoxazole on morbidity and mortality among people with HIV.
Research areas
- Clinical care
- HIV/AIDS
- Infectious disease
- Tuberculosis
Disciplines
- Epidemiology
- Medicine
- Operational research
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Selected publications
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Development of a Standardized Screening Rule for Tuberculosis in People Living with HIV in Resource-Constrained Settings: Individual Participant Data Meta-analysis of Observational Studies
Getahun, H.; Kittikraisak, W.; Heilig, C.M.; Corbett, E.L.; Ayles, H.; Cain, K.P.; Grant, A.D.; Churchyard, G.J.; Kimerling, M.; Shah, S.; Lawn, S.D.; Wood, R.; Maartens, G.; Granich, R.; Date, A.A.; Varma, J.K.
Plos Medicine, 2011; 8(1)
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Tuberculosis outcomes and drug susceptibility in individuals exposed to isoniazid preventive therapy in a high HIV prevalence setting.
van Halsema, C.L.; Fielding, K.L.; Chihota, V.N.; Russell, E.C.; Lewis, J.J.; Churchyard, G.J.; Grant, A.D.;
AIDS, 2010; 24(7):1051-5
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Adverse events with isoniazid preventive therapy: experience from a large trial.
Grant, A.D.; Mngadi, K.T.; van Halsema, C.L.; Luttig, M.M.; Fielding, K.L.; Churchyard, G.J.;
AIDS, 2010; 24 Suppl 5:S29-36
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Tuberculosis among people with HIV infection in the United Kingdom: opportunities for prevention?
Grant, A.D.; Bansi, L.; Ainsworth, J.; Anderson, J.; Delpech, V.; Easterbrook, P.; Fisher, M.; Gazzard, B.; Gilson, R.; Gompels, M.; Hill, T.; Johnson, M.; Leen, C.; Orkin, C.; Phillips, A.N.; Porter, K.; Post, F.; Walsh, J.; Sabin, C.A.; United Kingdom Collaborative HIV Cohort Study Group, .;
AIDS, 2009; 23(18):2507-15
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Managing drug resistant tuberculosis.
Grant, A.; Gothard, P.; Thwaites, G.;
BMJ, 2008; 337:a1110
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Evaluation of the WHO criteria for antiretroviral treatment failure among adults in South Africa.
Mee, P.; Fielding, K.L.; Charalambous, S.; Churchyard, G.J.; Grant, A.D.;
AIDS, 2008; 22(15):1971-1977
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Isoniazid preventive therapy and risk for resistant tuberculosis.
Balcells, M.E.; Thomas, S.L.; Godfrey-Faussett, P.; Grant, A.D.;
Emerg Infect Dis, 2006; 12(5):744-51
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Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-infected men in South Africa: a novel randomized incremental recruitment study.
Grant, A.D.; Charalambous, S.; Fielding, K.L.; Day, J.H.; Corbett, E.L.; Chaisson, R.E.; De Cock, K.M.; Hayes, R.J.; Churchyard, G.J.;
JAMA, 2005; 293(22):2719-25
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