Alison Grant MBBS MSc PhD DTM&H
- Alison Grant's Contacts
- Room 301
- Keppel Street
- WC1E 7HT
- T: +44 20 7927 2304
- F: +44 20 7927 2739
Alison Grant's Background
I trained initially as a physician specialising in infectious and tropical diseases and HIV medicine, and continue to work in HIV medicine in London. I studied epidemiology at LSHTM with particular interests in care for people with HIV in developing countries.
Alison Grant's Affiliation
Alison Grant's Teaching
I teach clinical tropical medicine, epidemiology and HIV/AIDS, particularly to students on MSc Tropical Medicine and International Health, and the LSHTM Diplomas in Tropical Medicine and Hygiene (in London and in East Africa).
Alison Grant's Research
My main research interest is care for people with HIV in developing countries, particularly preventive interventions. Current major projects include a cluster randomised trial investigating a point-of-care TB test and treat algorithm for people with advanced HIV disease in South Africa; evaluation of South African national roll-out of Xpert MTB/RIF, a new TB diagnostic test replacing smear microscopy; investigation of how best to use Xpert MTB/RIF among people attending clinics for HIV care; a cluster-randomised trial of an intervention to improve integration of TB and HIV care in primary health clinics; and the effect of community-wide TB preventive therapy among gold miners. In collaboration with colleagues in South Africa, I have been involved with the design, implementation and evaluation of an HIV care programme in workplace and community settings.
I supervise research degree students working on use of Xpert MTB/RIF in South Africa; causes of death among people starting ART in South Africa; reasons for loss to follow-up among people taking ART in Zimbabwe; and tuberculosis in Cambodia.
I did field work for my PhD on the clinical epidemiology of HIV disease at Projet RETRO-CI, Abidjan, Côte d'Ivoire, where I was also involved in a study of the effect of cotrimoxazole on morbidity and mortality among people with HIV.
- Clinical care
- Implementation research
- Randomised controlled trials
- Operational research
Disease and Health Conditions
- Infectious disease
- Europe & Central Asia (all income levels)
- Sub-Saharan Africa (all income levels)
- South Africa
- United Kingdom
- clinical epidemiology
Viral suppression following switch to second-line antiretroviral therapy: associations with NRTI resistance and 'sub-therapeutic' drug concentrations prior to switch.
Johnston, V.; Cohen, K.; Wiesner, L.; Morris, L.; Ledwaba, J.; Fielding, K.L.; Charalambous, S.; Churchyard, G.; Phillips, A.; Grant, A.D.;
J Infect Dis, 2014; 209(5):711-20
A trial of mass isoniazid preventive therapy for tuberculosis control.
Churchyard, G.J. ; Fielding, K.L. ; Lewis, J.J. ; Coetzee, L. ; Corbett, E.L. ; Godfrey-Faussett, P. ; Hayes, R.J. ; Chaisson, R.E. ; Grant, A.D. ; Thibela TB Study Team, . ;
N Engl J Med, 2014; 370(4):301-10
Development of a Standardized Screening Rule for Tuberculosis in People Living with HIV in Resource-Constrained Settings: Individual Participant Data Meta-analysis of Observational Studies
Getahun, H.; Kittikraisak, W.; Heilig, C.M.; Corbett, E.L.; Ayles, H.; Cain, K.P.; Grant, A.D.; Churchyard, G.J.; Kimerling, M.; Shah, S.; Lawn, S.D.; Wood, R.; Maartens, G.; Granich, R.; Date, A.A.; Varma, J.K.
Plos Medicine, 2011; 8(1):e1000391
Tuberculosis outcomes and drug susceptibility in individuals exposed to isoniazid preventive therapy in a high HIV prevalence setting.
van Halsema, C.L.; Fielding, K.L.; Chihota, V.N.; Russell, E.C.; Lewis, J.J.; Churchyard, G.J.; Grant, A.D.;
AIDS, 2010; 24(7):1051-5
Tuberculosis among people with HIV infection in the United Kingdom: opportunities for prevention?
Grant, A.D.; Bansi, L.; Ainsworth, J.; Anderson, J.; Delpech, V.; Easterbrook, P.; Fisher, M.; Gazzard, B.; Gilson, R.; Gompels, M.; Hill, T.; Johnson, M.; Leen, C.; Orkin, C.; Phillips, A.N.; Porter, K.; Post, F.; Walsh, J.; Sabin, C.A.; United Kingdom Collaborative HIV Cohort Study Group, .;
AIDS, 2009; 23(18):2507-15
Evaluation of the WHO criteria for antiretroviral treatment failure among adults in South Africa.
Mee, P.; Fielding, K.L.; Charalambous, S.; Churchyard, G.J.; Grant, A.D.;
AIDS, 2008; 22(15):1971-1977
Isoniazid preventive therapy and risk for resistant tuberculosis.
Balcells, M.E.; Thomas, S.L.; Godfrey-Faussett, P.; Grant, A.D.;
Emerg Infect Dis, 2006; 12(5):744-51
Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-infected men in South Africa: a novel randomized incremental recruitment study.
Grant, A.D.; Charalambous, S.; Fielding, K.L.; Day, J.H.; Corbett, E.L.; Chaisson, R.E.; De Cock, K.M.; Hayes, R.J.; Churchyard, G.J.;
JAMA, 2005; 293(22):2719-25
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