Alison Grant MBBS MSc PhD DTM&H

Professor of International Health


I trained initially as a physician specialising in infectious and tropical diseases and HIV medicine, and continue to work in HIV medicine in London. I studied epidemiology at LSHTM with particular interests in care for people with HIV in developing countries.




I teach epidemiology, HIV medicine, TB and clinical tropical medicine, particularly to students on MSc Tropical Medicine and International Health, and the LSHTM Diplomas in Tropical Medicine and Hygiene (in London and in East Africa).


My main research interest is improving care for people with HIV in developing countries, and preventing TB. Current major projects include a cluster randomised trial investigating a point-of-care TB test and treat algorithm for people with advanced HIV disease in South Africa; evaluation of South African national roll-out of Xpert MTB/RIF, a new TB diagnostic test replacing smear microscopy; investigation of how best to use Xpert MTB/RIF among people attending clinics for HIV care; linkage to care after a rifampicin-resistant Xpert MTB/RIF result in South Africa; and a trial comparing a single round of weekly isoniazid/rifapentine to periodic treatment is in development. In collaboration with colleagues in South Africa, I have been involved with the design, implementation and evaluation of an HIV care programme in workplace and community settings.

As the programme lead, I am developing a programme of tuberculosis research at the Africa Centre, KwaZulu-Natal, South Africa.

I supervise research degree students working on use of Xpert MTB/RIF in South Africa, and causes of death among people starting ART in South Africa.

Research areas

  • Clinical care
  • Clinical trials
  • Evaluation
  • Implementation research
  • Randomised controlled trials


  • Epidemiology
  • Medicine
  • Operational research

Disease and Health Conditions

  • Infectious disease
  • Tuberculosis


  • Europe & Central Asia (all income levels)
  • Sub-Saharan Africa (all income levels)


  • South Africa
  • United Kingdom

Other interests

  • Diagnostics,
  • clinical epidemiology
  • epidemiology
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