Patricia Gorak-Stolinska BSc PhD
- Immunology Unit,South Courtyard Room 494
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: 020 7927 2080
- F: 020 7927 2807
Patricia first joined the School in 1994 as a research Assistant to Prof. Paul Kaye, working on costimulatory molecules and marginal zone macrophages in a model for Leishmania donvani. After which she moved to the Dept. of Immunology Kings College London to work on Human CD4 and CD8 T cell subsets. In 2002 after completing her PhD Thesis on T cell Apoptosis at Guy's Kings and St. Thomas' School of Medicine, she returned to the school as a research fellow working on immunity to mycobacteria, in the lab of Prof Hazel Dockrell.
Patricia is currently the Deputy Course Director for the MSc Infectious Diseases (by Distance Learning).
Affiliation
Teaching
Deputy course Director for the DL MSc Infectious Diseases. Also, Projects organiser and currently a module organiser for Parasitology.
Research
Patricia’s main research interest is the study of T cell mediated immunity. Her particular interest is immune responses following vaccination and protective immune responses to TB. Currently she is supervising a PhD student looking at cross reactive mycobacterial antigens and cytokine signatures following BCG vaccination.Research areas
- T-cell immunology
- Vaccines
Disciplines
- Immunoepidemiology
- Immunology
Disease and Health Conditions
- Infectious disease
- Tuberculosis
Other interests
- BCG Vaccination
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Selected publications
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Persistence of the immune response induced by BCG vaccination
Weir, R.E.; Gorak-Stolinska, P.; Floyd, S.; Lalor, M.K.; Stenson, S.; Branson, K.; Blitz, R.; Ben-Smith, A.; Fine, P.E.M.; Dockrell, H.M.
BMC Infectious Diseases, 2008; 8
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BCG Vaccination: Epidemiology and Immunology
Dockrell, HM; Gorak-Stolinska, P; Rodrigues, LC;
in 'Handbook of Tuberculosis' Kaufmann, S; van Helden, P(2008) Wiley-VCH (Weinheim)
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BCG associated upregulation of activation markers in human T cells
Gorak-Stolinska, P.; Ben-Smith, A.; Weir, R.E.; Lalor, M.K.; Fine, P.E.M.; Dockrell, H.M.
Immunology, 2007; 120:76-76
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The PPD-specific T-cell clonal response in UK and Malawian subjects following BCG vaccination: A new repertoire evolves over 12 months
Bennett, A. R.; Gorak-Stolinska, P.; Ben-Smith, A.; Floyd, S.; de Lara, C. M.; Weir, R. E.; Lalor, M. K.; Makamo, K.; Msiska, G. K.; Crampin, A. C.; Fine, P. E. M.; Dockrell, H. M.; Beverley, P. C. L.
Vaccine, 2006; 24(14):2617-2626
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Immunogenicity of Danish-SSI 1331 BCG vaccine in the UK: Comparison with Glaxo-Evans 1077 BCG vaccine
Gorak-Stolinska, P.; Weir, R. E.; Floyd, S.; Lalor, M. K.; Stenson, S.; Branson, K.; Blitz, R.; Luke, S.; Nazareth, B.; Ben-Smith, A.; Fine, P. E. M.; Dockrell, H. M.
Vaccine, 2006; 24(29-30):5726-5733
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A role for tumor necrosis factor-alpha in remodeling the splenic marginal zone during Leishmania donovani infection
Engwerda, C. R.; Ato, M.; Cotterell, S. E.; Mynott, T. L.; Tschannerl, A.; Gorak-Stolinska, P. M.; Kaye, P. M.
American Journal of Pathology, 2002; 161(2):429-37
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Activation-induced cell death in human T cells is a suicidal process regulated by cell density but superantigen induces T cell fratricide.
Gorak-Stolinska, P.; Kemeny, D.M.; Noble, A.;
Cell Immunol, 2002; 219(2):98-107
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Activation-induced cell death of human T-cell subsets is mediated by Fas and granzyme B but is independent of TNF-alpha.
Gorak-Stolinska, P.; Truman, J.P.; Kemeny, D.M.; Noble, A.;
J Leukoc Biol, 2001; 70(5):756-66
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