Dr Antonio Gasparrini BSc MSc PhD

Lecturer in Biostatistics and Epidemiology

• Affiliation
• Teaching
• Research
• Publications

• 
• Room G36
• LSHTM
• Keppel Street
• London
• WC1E 7HT
• T: 0044 (0)20 79272406

I joined LSHTM in October 2007, and I am currently part of the Social & Environmental Health Research Department. After graduating in Biology at the University of Florence (Italy) with a thesis on occupational exposure and biological monitoring, I worked for 4 years as epidemiologist and statistician at the Occupational-Environmental Epidemiology Unit, Centre for Study and Prevention of Cancer (CSPO) in Florence. I attended a MSc in Biostatistics at the University of Bologna in 2005 and I concluded a 3-years post-graduate School of Biometry and Medical Statistics at the University of Milan in 2009. I concluded a PhD on Medical Statistics at LSHTM in September 2011.

Affiliation

• Department of Social and Environmental Health Research
• Department of Medical Statistics

Teaching

I am one of the practical group leaders in the Basic Statistics module of the Public Health MSc for PHP. At the beginning of the academic year I'm also involved in teaching on the Basic Math sessions for new students. I co-organize the lecture and practical on time-series within the Environmental Epidemiology module of the MSc in Public Health, and within the Advanced Statistical Modelling module of the MSc in Medical Statistics.

Research

My research interests mainly centre on statistical methods and study designs in environmental epidemiology.

Current research

I am currently involved in a methodological project with the aim to clarify and develop statistical methods to investigate the associations between environmental stressors and health events from time series data. I have also received a 3-years MRC-funded fellowship to advance this research, focusing in particular on:

• extending further distributed lag non-linear models, a modelling framework to specify and interpret non-linear and delayed effects in time series data. The aim is to extend this methodology beyond time-series analysis, providing a unified framework to describe and investigate delayed effects, exposure-time-response relationships and latency.

• developing multivariate meta-analytic techniques to synthesize complex relationships in two stage analysis for multi-site studies, with a focus on non-linear dependencies and distributed lag relationships.

Software development

Concurrently with my research activities, I implemented these statistical methodologies in two packages within the software environment R:

• the package dlnm (with related vignette) performs distributed lag non-linear models in time series data.

• the package mvmeta runs multivariate meta-analysis and meta-regression.

Citizenship

I am part of the Centre for Statistical Modelling, which promotes research and training on statistical methods within LSHTM, as co-ordinator for two themes (time series and statistical computing). In particular, I am responsible for the activities of the Centre about the R software. I also coordinate the Environmental and Health Research Group (EHRG).

Other projects

• Passive and active smoke: short-term effects of smoke-free bans on myocardial infarction risk, exposure assessment, environmental tobacco smoke markers, evaluation of quitting smoking intervention, assessment of state-wide smoke-free law.

• Asbestos: analysis and predictions of asbestos-related mortality in a historical cohort of exposed workers.

• Air pollution: traffic-related air pollution and respiratory symptoms in children, health effects and risk of transport systems (HEARTS project).

• Risk assessment: integrated assessment of health risks from environmental stressors (INTARESE project), use of low quality water and improved irrigation system and management (SAFIR project).

• Selected publications

• The impact of heat waves on mortality.

  Gasparrini, A.; Armstrong, B.;

  Epidemiology, 2011; 22(1):68-73

• The effect of high temperatures on cause-specific mortality in England and Wales.

  Gasparrini, A.; Armstrong, B.; Kovats, S.; Wilkinson, P.;

  Occup Environ Med, 2011; 69(1):56-61

• Effects of Italian Smoking Regulation on Rates of Hospital Admission for Acute Coronary Events: A Country-Wide Study

  Barone-Adesi, F.; Gasparrini, A.; Vizzini, L.; Merletti, F.; Richiardi, L.

  Plos One, 2011; 6(3)

• Time series analysis on the health effects of temperature: Advancements and limitations.

  Gasparrini, A.; Armstrong, B.;

  Environ Res, 2010; 110(6):633-8

• Distributed lag non-linear models.

  Gasparrini, A.; Armstrong, B.; Kenward, M.G.;

  Stat Med, 2010; 29(21):2224-34

• On the relationship between smoking bans and incidence of acute myocardial infarction.

  Gasparrini, A.; Gorini, G.; Barchielli, A.;

  Eur J Epidemiol, 2009; 24(10):597-602

• Prediction of mesothelioma and lung cancer in a cohort of asbestos exposed workers.

  Gasparrini, A.; Pizzo, A.M.; Gorini, G.; Seniori Costantini, A.; Silvestri, S.; Ciapini, C.; Innocenti, A.; Berry, G.;

  Eur J Epidemiol, 2008; 23(8):541-6

• → View all Dr Antonio Gasparrini's publications

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