Chris Frost MA DipStat
- Room G34
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: 020 7 927 2242
- F: 020 7637 2853
I studied mathematics and statistics at Cambridge University. Prior to moving to the School in the early nineties I worked as a statistician at the Department of Preventive Medicine, St. Bartholomew's Medical College, London.
Affiliation
Teaching
I co-organise and teach on the term 1 module 'Foundations of Medical Statistics'.
Research
My methodological interests include measurement error, meta-analysis, longitudinal data and hierarchical modelling. Areas of application include Alzheimer's Disease, Huntington's Disease and asthma.Research areas
- Clinical trials
- Systematic reviews
Disciplines
- Statistics
Disease and Health Conditions
- Asthma
- Mental health
Other interests
- Dementia
- Neurology
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Selected publications
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Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
Tabrizi, S.J.; Scahill, R.I.; Durr, A.; Roos, R.A.C.; Leavitt, B.R.; Jones, R.; Landwehrmeyer, G.B.; Fox, N.C.; Johnson, H.; Hicks, S.L.; Kennard, C.; Craufurd, D.; Frost, C.; Langbehn, D.R.; Reilmann, R.; Stout, J.C.
Lancet Neurology, 2011; 10(1):31-42
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Linear mixed models for replication data to efficiently allow for covariate measurement error
Bartlett, J.W.; De Stavola, B.L.; Frost, C.;
Statistics in Medicine, 2009; 28(25):3158-78
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Prevalence of Angina in Women Versus Men. A Systematic Review and Meta-Analysis of International Variations Across 31 Countries.
Hemingway, H.; Langenberg, C.; Damant, J.; Frost, C.; Pyörälä, K.; Barrett-Connor, E.;
Circulation, 2008; 117(12):1526-36
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Optimizing the design of clinical trials where the outcome is a rate. Can estimating a baseline rate in a run-in period increase efficiency?
Frost, C.; Kenward, M.G.; Fox, N.C.;
Stat Med, 2008; 27(19):3717-31
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The effect of measurement error in risk factors that change over time in cohort studies: do simple methods overcorrect for 'regression dilution'?
Frost, C.; White, I.R.;
Int J Epidemiol, 2005; 34(6):1359-68
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The analysis of repeated 'direct' measures of change illustrated with an application in longitudinal imaging.
Frost, C.; Kenward, M.G.; Fox, N.C.;
Stat Med, 2004; 23(21):3275-3286
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Assessing the onset of structural change in familial Alzheimer's disease
Schott, J. M.; Fox, N. C.; Frost, C.; Scahill, R. I.; Janssen, J. C.; Chan, D.; Jenkins, R.; Rossor, M. N.
Annals of Neurology, 2003; 53(2):181-188
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Control of exposure to mite allergen and allergen-impermeable bed covers for adults with asthma
Woodcock, A.; Forster, L.; Matthews, E.; Martin, J.; Letley, L.; Vickers, M.; Britton, J.; Strachan, D.; Howarth, P.; Altmann, D.; Frost, C.; Custovic, A.
New England Journal of Medicine, 2003; 349(3):225-236
- → View all Chris Frost's publications
