Dr Helen Fletcher BSc PhD

Associate Professor in Immunology and Director, TB Centre


I gained a PhD in Medical Microbiology from the University of Leeds and became interested in tuberculosis (TB) in 1999 during my first postdoctoral position at University College London. In 2002 I moved to the Jenner Institute at the University of Oxford as an immunologist for the first-in-man trial of a new TB vaccine, MVA85A. After 10 years at the Jenner Institute I moved to the London School of Hygiene & Tropical Medicine to establish my group, based in the Immunology and Infection Department, which focuses on immune correlates and the host response to TB vaccination. In 2015 I became Director of the TB Centre: http://tb.lshtm.ac.uk/ at the London School of Hygiene & Tropical Medicine and in 2016 I became co-chair of the T-cell Immunology working group for the Collaboration for TB Vaccine Discovery (CTVD) at the Bill & Melinda Gates Foundation.




I am co-organizer of the Vaccine Immunology MSc module with Eleanor Riley and I am a tutor on the Distance Learning programme


My interests are in vaccine development for TB and identification of immune mechanisms important for protection from TB





Research areas

  • Disease control
  • Global Health
  • Immunisation
  • Innate immunity
  • T-cell immunology
  • Vaccines


  • Bioinformatics
  • Immunology
  • Vaccinology

Disease and Health Conditions

  • Infectious disease
  • Malaria
  • Tuberculosis


  • Sub-Saharan Africa (all income levels)


  • Gambia, The
  • Senegal
  • South Africa
  • Thailand

Other interests

  • BCG
  • BCG Vaccination
  • Cellular Immunology
  • Immunization,Vaccine
  • Immunogenicity
  • Macrophage
  • Malaria Centre
  • Microarray Technology
  • Microarrays
  • Next Generation Sequencing
  • TB Centre
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