Alison Elliott MA MBBS MD DTH&H FRCP

- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: 0207 927 2116
Alison Elliott is a physician, specialising in infectious diseases and tropical medical research. After a degree in Natural Sciences and medical training in the UK she went to Zambia in 1988, and undertook early studies on the interaction between tuberculosis and HIV infection. Between 1992 and 1995 she undertook and infectious diseases fellowship in the USA, with research on the immunology of tuberculosis at the National Jewish Center in Denver, Colorado. Since 1996 she has been working in Uganda, supported by Wellcome Trust funding, at the Medical Research Council Unit at the Uganda Virus Research Institute (UVRI), where she is head of the Co-infection Studies Programme.
Affiliation
Teaching
Alison's main "teaching" activity is in research capacity building in Uganda. She currently leads the Wellcome Trust funded Makerere-UVRI research training programme in Infection and Immunity (MUII) which aims to attract bright young Ugandans to science and support them to develop an internationally competitive research career in the field of Infection and Immunity. This programme is a collaboration between the Uganda Virus Research Institute, Makerere University, LSHTM and Cambridge University. Activities include Open Days for schools, undergraduate internships, and a Masters, PhD and post-doctoral fellowship scheme; as well as a new short course in Immunology (Immunology in the Tropics) and a series of Hot Topics seminars presented by scientists who are world leaders in their fields as they visit Uganda.
Research
Alison's research interests focus on the immuno-modulating effects of chronic infections. After early studies on HIV and tuberculosis she developed an interest in the immunomodulating effects of helminths. Current research particularly addresses the effects of maternal helminth infection, and helminth infections in young children, on outcomes in childhood. New studies planned for the forthcoming five-year period will address the impact of helminth infections on responses to vaccines, to microbial pathogens and to allergens. She is also interested in the relationship between maternal immune responses and immunological and infectious disease outcomes in the offspring.
Research areas
- Child health
- Clinical trials
- Helminths
Disciplines
- Epidemiology
- Immunoepidemiology
- Immunology
- Medicine
Disease and Health Conditions
- Tuberculosis
-
Selected publications
-
Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial.
Webb, E.L.; Mawa, P.A.; Ndibazza, J.; Kizito, D.; Namatovu, A.; Kyosiimire-Lugemwa, J.; Nanteza, B.; Nampijja, M.; Muhangi, L.; Woodburn, P.W.; Akurut, H.; Mpairwe, H.; Akello, M.; Lyadda, N.; Bukusuba, J.; Kihembo, M.; Kizza, M.; Kizindo, R.; Nabulime, J.; Ameke, C.; Namujju, P.B.; Tweyongyere, R.; Muwanga, M.; Whitworth, J.A.; Elliott, A.M.;
Lancet, 2011; 377(9759):52-62
-
Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results.
Mpairwe, H.; Webb, E.L.; Muhangi, L.; Ndibazza, J.; Akishule, D.; Nampijja, M.; Ngom-Wegi, S.; Tumusime, J.; Jones, F.M.; Fitzsimmons, C.; Dunne, D.W.; Muwanga, M.; Rodrigues, L.C.; Elliott, A.M.;
Pediatr Allergy Immunol, 2011;
-
Effectiveness of the Standard WHO Recommended Retreatment Regimen (Category II) for Tuberculosis in Kampala, Uganda: A Prospective Cohort Study.
Jones-López, E.C. ; Ayakaka, I. ; Levin, J. ; Reilly, N. ; Mumbowa, F. ; Dryden-Peterson, S. ; Nyakoojo, G. ; Fennelly, K. ; Temple, B. ; Nakubulwa, S. ; Joloba, M.L. ; Okwera, A. ; Eisenach, K.D. ; McNerney, R. ; Elliott, A.M. ; Ellner, J.J. ; Smith, P.G. ; Mugerwa, R.D. ;
PLoS Med, 2011; 8(3):e1000427
-
Effects of Deworming during Pregnancy on Maternal and Perinatal Outcomes in Entebbe, Uganda: A Randomized Controlled Trial.
Ndibazza, J.; Muhangi, L.; Akishule, D.; Kiggundu, M.; Ameke, C.; Oweka, J.; Kizindo, R.; Duong, T.; Kleinschmidt, I.; Muwanga, M.; Elliott, A.M.;
Clin Infect Dis, 2010;
-
Effects of maternal and infant co-infections, and of maternal immunisation, on the infant response to BCG and tetanus immunisation.
Elliott, A.M.; Mawa, P.A.; Webb, E.L.; Nampijja, M.; Lyadda, N.; Bukusuba, J.; Kizza, M.; Namujju, P.B.; Nabulime, J.; Ndibazza, J.; Muwanga, M.; Whitworth, J.A.;
Vaccine, 2010;
-
The impact of helminths on the response to immunization and on the incidence of infection and disease in childhood in Uganda: design of a randomized, double-blind, placebo-controlled, factorial trial of deworming interventions delivered in pregnancy and early childhood [ISRCTN32849447].
Elliott, A.M.; Kizza, M.; Quigley, M.A.; Ndibazza, J.; Nampijja, M.; Muhangi, L.; Morison, L.; Namujju, P.B.; Muwanga, M.; Kabatereine, N.; Whitwortha, J.A.;
Clin Trials, 2007; 4(1):42-57
-
A Randomized, Double-Blind, Placebo-Controlled Trial of the Use of Prednisolone as an Adjunct to Treatment in HIV-1-Associated Pleural Tuberculosis.
Elliott, A.M.; Luzze, H.; Quigley, M.A.; Nakiyingi, J.S.; Kyaligonza, S.; Namujju, P.B.; Ducar, C.; Ellner, J.J.; Whitworth, J.A.; Mugerwa, R.; Johnson, J.L.; Okwera, A.;
J Infect Dis , 2004; 190 (5 ):869-78
-
Helminth Infection Is Not Associated with Faster Progression of HIV Disease in Coinfected Adults in Uganda.
Brown, M.; Kizza, M.; Watera, C.; Quigley, M.A.; Rowland, S.; Hughes, P.; Whitworth, J.A.; Elliott, A.M.;
J Infect Dis, 2004; 190(10):1869-79
- → View all Alison Elliott's publications
