Shah Ebrahim BM BS MSc DM FRCP FFPHM

- Room 116
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: +44 (0)20 7927 2215
- F: +44 (0)20 7927 2282
I studied medicine at Nottingham University (1970-5), including an inter-collated degree in community medicine, and obtained an MSc in epidemiology from LSHTM in 1981, and a DM in 1985, holding a Wellcome Trust fellowship in clinical epidemiology during this time. I trained in primary care and subsequently in geriatric medicine and have held chairs in geriatric medicine (London & Barts 1989-92), clinical epidemiology (Royal Free, 1992-1998), and epidemiology of ageing (University of Bristol, 1998-2005). I am a visiting fellow at the University of Bristol and visiting professor at University College London. I am co-editor of the International Journal of Epidemiology and coordinating editor of the Cochrane Heart Group. I chaired the Wellcome Trust Populations & Public Health funding committee (2005-7) and am a member of the Wellcome Pathogens, Immunology and Population Health Strategy Committee. I was a non-executive board member of National Institute for Health and Clinical Excellence (NICE) (2005-8) and am a member of the NICE Internatinoal advisory committee. In 2008 moved to New Delhi following awards of Wellcome Trust grants to work with Public Health Foundation of India to build capacity for public health activities and to establish a south Asia network for chronic disease research. I joined LSHTM in October 2005.
Affiliation
Teaching
I currently teach extended epidemiology and public health courses when I am in London.
Research
I set up the British Women's Heart & Health Study, a cohort of over 4000 women in 23 British towns, in 1998 which mirrors the design of the British Regional Heart Study of men, on which I also work. This study has generated a large body of work on the life-course determinants of insulin resistance, and with George Davey Smith, I am currently using Mendelian randomization designs to examine the unconfounded effects of environmental factors on risk of common diseases. I am also interested in the ways migration influences the development of cardiovascular risk factors and am running a large Wellcome Trust funded study in India. As part of my Wellcome Trust grant for work in India am now setting up a range of studies concerned with monitoring cardiovascular risk factors and interventions to reduce cardiovascular disease in India.
Research areas
- Ageing
- Public health
- Systematic reviews
Disciplines
- Epidemiology
- Genetics
- Life-course epidemiology
- Medicine
Disease and Health Conditions
- Cardiovascular disease
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Selected publications
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Fasting Blood Glucose and the Risk of Stroke and Myocardial Infarction.
Sung, J.; Song, Y.M.; Ebrahim, S.; Lawlor, D.A.;
Circulation, 2009; 119(6):812-9
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Complex interventions to improve physical function and maintain independent living in elderly people: a systematic review and meta-analysis.
Beswick, A.D.; Rees, K.; Dieppe, P.; Ayis, S.; Gooberman-Hill, R.; Horwood, J.; Ebrahim, S.;
Lancet, 2008; 371(9614):725-35
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Alcohol dehydrogenase type 1C (ADH1C) variants, alcohol consumption traits, HDL-cholesterol and risk of coronary heart disease in women and men: British Women's Heart and Health Study and Caerphilly cohorts.
Ebrahim, S.; Lawlor, D.A.; Shlomo, Y.B.; Timpson, N.; Harbord, R.; Christensen, M.; Baban, J.; Kiessling, M.; Day, I.; Gaunt, T.; Davey Smith, G.;
Atherosclerosis, 2007; 196(2):871-8
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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
Frayling, T.M.; Timpson, N.J.; Weedon, M.N.; Zeggini, E.; Freathy, R.M.; Lindgren, C.M.; Perry, J.R.B.; Elliott, K.S.; Lango, H.; Rayner, N.W.; Shields, B.; Harries, L.W.; Barrett, J.C.; Ellard, S.; Groves, C.J.; Knight, B.; Patch, A.M.; Ness, A.R.; Ebrahim, S.; Lawlor, D.A.; Ring, S.M.; Ben-Shlomo, Y.; Jarvelin, M.R.; Sovio, U.; Bennett, A.J.; Melzer, D.; Ferrucci, L.; Loos, R.J.F.; Barroso, I.; Wareham, N.J.; Karpe, F.; Owen, K.R.; Cardon, L.R.; Walker, M.; Hitman, G.A.; Palmer, C.N.A.; Doney, A.S.F.; Morris, A.D.; Smith, G.D.; Hattersley, A.T.; McCarthy, M.I.
Science, 2007; 316(5826):889-894
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Independent associations of fasting insulin, glucose, and glycated haemoglobin with stroke and coronary heart disease in older women
Lawlor, D.A.; Fraser, A.; Ebrahim, S.; Smith, G.D.
PLoS Med, 2007; 4(8):e263
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What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?
Davey Smith, G.; Ebrahim, S.;
British Medical Journal, 2005; 330(7499):1076-9
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C-reactive protein and its role in metabolic syndrome: mendelian randomisation study.
Timpson, N.J.; Lawlor, D.A.; Harbord, R.M.; Gaunt, T.R.; Day, I.N.; Palmer, L.J.; Hattersley, A.T.; Ebrahim, S.; Lowe, G.D.; Rumley, A.; Davey Smith, G.;
Lancet, 2005; 366(9501):1954-9
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