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Prof Ian Douglas

Professor of Pharmacoepidemiology

United Kingdom

I am an epidemiologist, currently funded by GlaxoSmithKline. I initially studied physiology at BSc and PhD level in Manchester. Since then, I spent several years at the UK Medicines & Healthcare Products Regulatory Agency and in the pharmaceutical industry investigating adverse effects of drugs - both in clinical trials and post-marketing. I completed the MSc in epidemiology at LSHTM in 2005.

Affiliations

Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Centres

Centre for Data and Statistical Science for Health

Teaching

Most of my teaching is split between the LSHTM pharmacoepidemiology range of short courses and the MSc in Epidemiology,

Research

I am interested in pharmacoepidemiology, and in particular, how large electronic health record databases can be used to investigate the effects of drugs - both harmful and beneficial. I am exploring methodologies to minimize some of the biases inherent in the research of drug effects, and my main current areas of interest include case-only approaches to study design, the use of non-interventional data to estimate intended treatment effects, quantitative bias analysis, and the application of high dimensional propensity scores in electronic health data.

Selected Publications

Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK.
BHASKARAN, K; DOS-SANTOS-SILVA, I; LEON, DA; DOUGLAS, IJ; SMEETH, L;
2018
The lancet. Diabetes & endocrinology
Changing use of antidiabetic drugs in the UK: trends in prescribing 2000-2017.
WILKINSON, S; DOUGLAS, I; Stirnadel-Farrant, H; Fogarty, D; Pokrajac, A; SMEETH, L; TOMLINSON, L;
2018
BMJ open
Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort.
Yates, TA; TOMLINSON, LA; BHASKARAN, K; LANGAN, S; THOMAS, S; SMEETH, L; DOUGLAS, IJ;
2017
PLoS medicine
Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015.
SINNOTT, S-J; SMEETH, L; WILLIAMSON, E; DOUGLAS, IJ;
2017
BMJ (Clinical research ed)
Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study.
BRAUER, R; BHASKARAN, K; Chaturvedi, N; Dexter, DT; SMEETH, L; DOUGLAS, I;
2015
PLoS medicine
Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults.
BHASKARAN, K; DOUGLAS, I; FORBES, H; DOS-SANTOS-SILVA, I; LEON, DA; SMEETH, L;
2014
Lancet
Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.
DOUGLAS, IJ; EVANS, SJ W; Hingorani, AD; Grosso, AM; Timmis, A; Hemingway, H; SMEETH, L;
2012
BMJ (Clinical research ed)
The risk of fractures associated with thiazolidinediones: a self-controlled case-series study.
DOUGLAS, IJ; EVANS, SJ; POCOCK, S; SMEETH, L;
2009
PLoS medicine
Rapid Safety Assessment of SARS-CoV-2 Vaccines in EU Member States using Electronic Health Care Data Sources (COVID Vaccine Monitor-CVM study): Final Study Report for WP3 (electronic health record data)
Durán, CE; Messina, D; Gini, R; Riefolo, F; Aragón, M; Belitser, S; Bissacco, CA; Bots, SH; De Burgos, A; Carreras-Martínez, JJ; Correcher-Martínez, E; DOUGLAS, IJ; Garcia-Poza, P; Girardi, A; Herings, R; Hoxhaj, V; Huerta, C; Hyeraci, G; Ientile, V; Ingrasciotta, Y; Limoncella, G; Lupattelli, A; Maglanoc, L; Martin, I; Martin, M; ... Sturkenboom, M.
2023
Zenodo
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