Dr Mary DeSilva BA MSc PhD
Epidemiologist working in global mental health research with the ultimate goal of reducing the treatment gap for mental disorders in low resource settings, while protecting human rights.

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- LSHTM
- Keppel Street
- London
- WC1E 7HT
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I read Biological Anthropology at Cambridge (BA, 1999), and went on to complete an MSc Epidemiology and PhD in Epidemiology at LSHTM. My PhD explored the association between social capital and maternal common mental disorders in low and middle income countries (LMIC). After my PhD I was awarded an MRC/ESRC Interdisciplinary Post-Doctoral Fellowship to continue global mental health research, mentored by Vikram Patel. I now hold an LSHTM/Wellcome Trust fellowship.
Affiliation
- Department of Nutrition and Public Health Intervention Research
- Faculty of Epidemiology and Population Health
Teaching
Along with colleagues Alex Cohen and Vikram Patel, I am involved in the development of an exciting new MSc in Global Mental Health (joint with the Institute of Psychiatry), to be launched in Sept 2012.
I am a course organiser for the Global Mental Health Module, and currently also teach on the Basic Epidemiology and Design and Analysis of Epidemiological Studies study modules. I tutor on the MSc Epidemiology MSc and supervise PhD students in the field of global mental health. I am also deputy departmental research degrees co-ordinator for NPHIR.
Research
I am Deputy Director of the Centre for Global Mental Health, a research partnership between LSHTM and Kings Health Partners, and am on the steering group of the Centre for Disability at LSHTM. I a member of the Advisory Board for the Global Movement for Mental Health, which was launched after the 2007 Lancet Series on Global Mental Health. The Movement seeks to use advocacy to scale up evidence based treatments for mental illnesses, particularly in low and middle income countries.
I am currently predominantly working on two research projects.
The first is a DfID funded 6 year project entitled PRIME (PRogramme for Improving Mental health carE). The goal of PRIME is to generate world-class research evidence on the implementation and scaling up of treatment programmes for priority mental disorders in primary and maternal health care contexts in low resource settings. PRIME is a consortium of research institutions and Ministries of Health in five countries in Asia and Africa (Ethiopia, India, Nepal, South Africa & Uganda), with partners comprising the LSHTM, Institute of Psychiatry, Basic Needs and the WHO.
The second project is an NIMH funded 5 year project called SHARE (the South Asian Hub for Advocacy, Research and Education on mental health), a collaborative network of institutions in South Asia, which will carry out and utilize research that answers policy relevant questions related to reducing the treatment gap for mental disorders in the region. As part of this we will be conducting 2 RCTs (in India and Pakistan), evaluating the effectiveness of peer-counsellors for maternal depression.
I have recently worked on a number of other Global Mental Health projects including: designing a routine monitoring and evaluation system to assess the effectiveness of an NGO-run mental health treatment program in Nigeria; analysis of data from the MANAS trial of a stepped care intervention for the treatment of common mental disorders in primary care in India; and systematic reviews of the effect of interventions to improve the lives of people with mental disorders in low and middle income countries on their economic status and social functioning.
A consistent theme throughout my work is the association between mental and physical health, with the premise that 'there is no health without mental health'. Projects include the impact of treating mental health problems in people who have chronic disease; the association between maternal mental health and child physical health and development in LMIC, and the relationship between mental illness and disability.
Research areas
- Child health
- Clinical trials
- Maternal health
- Systematic reviews
Disciplines
- Epidemiology
- Psychology
Disease and Health Conditions
- Disability
- Mental health
Regions
- South Asia
- Sub-Saharan Africa (all income levels)
- Sub-Saharan Africa (developing only)
Countries
- Ethiopia
- India
- Nepal
- Nigeria
- Pakistan
- South Africa
- Uganda
Other interests
- Cluster Randomised Trials
- Cochrane Reviews
- Community Based Health Agents
- Contextual Factors
- Developing countries
- Epidemiological Methods
- Maternal And Child Health
- Monitoring And Evaluation
- NCDs-Intervention Research
- Neglected Diseases
- epidemiology
- global health
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Selected publications
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Reducing the treatment gap for mental disorders: a WPA survey.
Patel, V.; Maj, M.; Flisher, A.J.; DE Silva, M.J.; Koschorke, M.; Prince, M.; WPA Zonal and Member Society Representatives*, .;
World Psychiatry, 2010; 9(3):169-76
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Effectiveness of an intervention led by lay health counsellors for depressive and anxiety disorders in primary care in Goa, India (MANAS): a cluster randomised controlled trial.
Patel, V.; Weiss, H.A.; Chowdhary, N.; Naik, S.; Pednekar, S.; Chatterjee, S.; De Silva, M.J.; Bhat, B.; Araya, R.; King, M.; Simon, G.; Verdeli, H.; Kirkwood, B.R.;
Lancet, 2010;
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Interventions for improving the psychosocial well-being of children affected by HIV and AIDS.
King, E.; De Silva, M.; Stein, A.; Patel, V.;
Cochrane Database Syst Rev, 2009; (2):CD006733
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Psychosocial interventions for the prevention of disability following traumatic physical injury.
De Silva, M.; Maclachlan, M.; Devane, D.; Desmond, D.; Gallagher, P.; Schnyder, U.; Brennan, M.; Patel, V.;
Cochrane Database Syst Rev, 2009; (4):CD006422
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Social capital and mental health: A comparative analysis of four low income countries.
De Silva, M.J.; Huttly, S.R.; Harpham, T.; Kenward, M.G.;
Soc Sci Med, 2007; 64(1):5-20
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Treatment and prevention of mental disorders in low-income and middle-income countries.
Patel, V.; Araya, R.; Chatterjee, S.; Chisholm, D.; Cohen, A.; De Silva, M.; Hosman, C.; McGuire, H.; Rojas, G.; van Ommeren, M.;
Lancet, 2007; 370(9591):991-1005
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Social capital and mental illness: a systematic review.
De Silva, M.J.; McKenzie, K.; Harpham, T.; Huttly, S.R.;
J Epidemiol Community Health, 2005; 59(8):619-27
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Psychometric and cognitive validation of a social capital measurement tool in Peru and Vietnam.
De Silva, M.J.; Harpham, T.; Tuan, T.; Bartolini, R.; Penny, M.E.; Huttly, S.R.;
Soc Sci Med, 2005; 62(4):941-53
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