Dr Jon Cuccui BSc MSc PhD

Research Fellow Pathogen Molecular Biology

Jon started at the LSHTM in September 2002. He was previously employed at St. Bartholomew's Hospital working on an ancient DNA extraction project. He attempted to extract human and Yersinia pestis DNA from the teeth of suspected plague victims who died in the 14th century. Other projects included looking into the genetic organisation and functional aspects of a putative metabolic island containing cobalamin synthesis and propanediol utilisation operons in Yersinia enterocolitica 8081.

He completed his Ph.D. in Professor Brendan Wren's laboratory carrying out signature tagged mutagenesis on Burkholderia pseudomallei.He completed his first Post Doc carrying out glycoengineering with Francisella tularensis and B. pseudomallei and is now continuing to work within the glycoengineering field.

 

Affiliation

Teaching

Distance learning M.Sc. Tutor and Examiner

Medical Microbiology M.Sc. Tutor, project supervisor, examiner and exam board member

Research

He is working on the O-antigen of Francisella tularensis and characterising the capsular polysaccharide of Burkholderia pseudomallei. He also continues to work on selected mutants identified during his PhD entitled 'The development of a refined signature tagged mutagenesis strategy for the identification of novel virulence determinants and vaccine candidates in Burkholderia pseudomallei.'

He is currently funded by a BBSRC LoLa grant to study various aspects of the epidemiology and pathogenicity of several pig pathogens including Streptococcus suis, Actinobacillus pleuropneumoniae, Haemphilus parasuis and Mycoplasma hyopneumoniae.

Research areas

  • Bacteria
  • Vaccines

Disciplines

  • Bacteriology
  • Genetic epidemiology
  • Genetics
  • Microbiology
  • Molecular biology

Disease and Health Conditions

  • Infectious disease

Other interests

  • Bacterial Infections
  • Biological Weapons
  • Burkholderia Pseudomallei
  • Conjugate Vaccines
  • Emerging Infectious Diseases
  • Francisella Tularensis
  • Glycoengineering
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