Patrick Corran BA (Mod) DPhil
- Room 238
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: +44 207 927 2294
- F: +44 207 927 2807
Retired from NIBSC 2010
Interests Malaria Immunology, Malaria Vaccines, Vaccine characterisaton
Affiliation
Teaching
Tutor for Distance Learning MSc in Infectious Diseases, ID102, module 2
MSc Immunology of Infectious Diseases
Research
Methods for the evaluation and control of malaria vaccine candidates
Standardisation of immunoassays of all kinds, particularly for malaria vaccine evaluation
Development of humoral immunity under conditions of natural transmission
Use of serological methods to assess tranmission intensity
Methods for the assessment of qualitative aspects of humoral immunity in response to natural infections and vaccination
Development of high-capacity multi-antigen methods for monitoring humoral immunity
Genetic factors associated with malaria susceptibility and resistance and how they influence immune phenotype
Research areas
- Vaccines
Disciplines
- Biochemistry
- Immunoepidemiology
- Immunology
Disease and Health Conditions
- Malaria
Other interests
- Immunization,Vaccine
- Malaria Centre
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Selected publications
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Profiling the Antibody Immune Response against Blood Stage Malaria Vaccine Candidates.
Gray, J.C.; Corran, P.H.; Mangia, E.; Gaunt, M.W.; Li, Q.; Tetteh, K.K.; Polley, S.D.; Conway, D.J.; Holder, A.A.; Bacarese-Hamilton, T.; Riley, E.M.; Crisanti, A.;
Clin Chem, 2007; 53(7):1244-53
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Serology: a robust indicator of malaria transmission intensity?
Corran, P.; Coleman, P.; Riley, E.; Drakeley, C.;
Trends Parasitol, 2007; 23(12):575-82
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Estimating medium- and long-term trends in malaria transmission by using serological markers of malaria exposure.
Drakeley, C.J.; Corran, P.H.; Coleman, P.G.; Tongren, J.E.; McDonald, S.L.; Carneiro, I.; Malima, R.; Lusingu, J.; Manjurano, A.; Nkya, W.M.; Lemnge, M.M.; Cox, J.; Reyburn, H.; Riley, E.M.;
Proc Natl Acad Sci U S A, 2005; 102(14):5108-13
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The fine specificity, but not the invasion inhibitory activity, of 19-kilodalton merozoite surface protein 1-specific antibodies is associated with resistance to malarial parasitemia in a cross-sectional survey in the gambia.
Corran, P.H.; O'Donnell, R.A.; Todd, J.; Uthaipibull, C.; Holder, A.A.; Crabb, B.S.; Riley, E.M.;
Infect Immun, 2004; 72(10):6185-9
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