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Prof Liz Corbett

Professor of Global Health

United Kingdom

Tel.
02079272136

I am a Clinical Epidemiologist with specialty training in infectious diseases. I have been with London School of Hygiene and Tropical Medicine for my Wellcome PhD Fellowship in South Africa (1996-99) and my subsequent Wellcome Fellowships in Zimbabwe (Feb 2001- Apr 2009) and Malawi (Apr 2009- Jul 2020). I lived in Africa until my return to UK in 2020. I still work closely with 2 TB and HIV research groups in Malawi (MLW and Kumuzu University of Health Sciences (KUHeS), now headed by Dr Augustine Choko and Dr Marriott Nliwasa, respectively. I have collaborative projects in Zimbabwe and Nigeria.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Centres

Centre for Evaluation
TB Centre

Teaching

Mainly distance-based teaching on the TB module.

Research

My main interest is in design and evaluation of diagnostic impact interventions, with my work contributing to LSHTM Research Excellence Framework case studies in 2014 (TB screening in people living with HIV) and 2021 (Making HIV self-testing available to millions as a diagnostic strategy for low and middle income countries). My cluster-randomised trial of active case-finding for TB (Corbett Lancet 2010: DETECTB trial) triggered international policy change with a Rapid Policy Update in 2011 and subsequent Guideline Development Group by World Health Organization (WHO) with updated Guidelines on Systematic Screening for Active TB Disease released in 2013 and 2021, providing the first updates since the 1970s. My work on HIV self-testing was recognized as fundamental in 3 WHO/UNAIDS Rapid Technical Updates (2011-14) and substantive Guidelines (2016, 2019). My work with Rashida Ferrand influenced adolescent HIV WHO Guidelines in 2012 and 2015.

Research Area
Epidemiology
Clinical guidelines
Clinical research
Clinical trials
Diagnostics
Randomised controlled trials
Disease and Health Conditions
HIV/AIDS
Tuberculosis
Respiratory diseases
Country
South Africa
Zimbabwe
Malawi
Nigeria
Zambia
Region
Sub-Saharan Africa (all income levels)

Selected Publications

Impact of Community-Wide Tuberculosis Active Case Finding and Human Immunodeficiency Virus Testing on Tuberculosis Trends in Malawi.
BURKE, RM; Nliwasa, M; Dodd, PJ; FEASEY, HR A; Khundi, M; Choko, A; Nzawa-Soko, R; Mpunga, J; WEBB, EL; FIELDING, K; MacPherson, P; CORBETT, EL;
2023
Clinical infectious diseases
Trial-of-antibiotics to assist tuberculosis diagnosis in symptomatic adults in Malawi (ACT-TB study): a randomised controlled trial.
Divala, TH; CORBETT, EL; Kandulu, C; Moyo, B; MacPherson, P; Nliwasa, M; French, N; Sloan, DJ; Chiume, L; Ndaferankhande, MJ; Chilanga, S; Majiga, ST; Odland, JØ; FIELDING, KL;
2023
The Lancet Global Health
Computer-aided X-ray screening for tuberculosis and HIV testing among adults with cough in Malawi (the PROSPECT study): A randomised trial and cost-effectiveness analysis.
MacPherson, P; WEBB, EL; Kamchedzera, W; Joekes, E; Mjoli, G; Lalloo, DG; Divala, TH; Choko, AT; BURKE, RM; Maheswaran, H; Pai, M; Squire, SB; Nliwasa, M; CORBETT, EL;
2021
PLoS medicine
Effect of peer-distributed HIV self-test kits on demand for biomedical HIV prevention in rural KwaZulu-Natal, South Africa: a three-armed cluster-randomised trial comparing social networks versus direct delivery.
Shahmanesh, M; Mthiyane, TN; Herbsst, C; NEUMAN, M; Adeagbo, O; MEE, P; Chimbindi, N; Smit, T; Okesola, N; Harling, G; McGrath, N; Sherr, L; SEELEY, J; Subedar, H; JOHNSON, C; Hatzold, K; TERRIS-PRESTHOLT, F; Cowan, FM; CORBETT, EL;
2021
BMJ global health
Effect of door-to-door distribution of HIV self-testing kits on HIV testing and antiretroviral therapy initiation: a cluster randomised trial in Malawi.
INDRAVUDH, PP; FIELDING, K; Chilongosi, R; Nzawa, R; NEUMAN, M; Kumwenda, MK; Nyirenda, R; JOHNSON, CC; Taegtmeyer, M; Desmond, N; Hatzold, K; CORBETT, EL;
2021
BMJ global health
Pragmatic economic evaluation of community-led delivery of HIV self-testing in Malawi.
INDRAVUDH, PP; FIELDING, K; SANDE, LA; Maheswaran, H; Mphande, S; Kumwenda, MK; Chilongosi, R; Nyirenda, R; JOHNSON, CC; Hatzold, K; CORBETT, EL; TERRIS-PRESTHOLT, F;
2021
BMJ global health
ART initiations following community-based distribution of HIV self-tests: meta-analysis and meta-regression of STAR Initiative data.
NEUMAN, M; FIELDING, KL; AYLES, H; Cowan, FM; HENSEN, B; INDRAVUDH, PP; JOHNSON, C; Sibanda, EL; Hatzold, K; CORBETT, EL;
2021
BMJ global health
Partner-delivered HIV self-test kits with and without financial incentives in antenatal care and index patients with HIV in Malawi: a three-arm, cluster-randomised controlled trial.
Choko, AT; FIELDING, K; JOHNSON, CC; Kumwenda, MK; Chilongosi, R; Baggaley, RC; Nyirenda, R; SANDE, LA; Desmond, N; Hatzold, K; NEUMAN, M; CORBETT, EL;
2021
The Lancet. Global health
Effect of community-led delivery of HIV self-testing on HIV testing and antiretroviral therapy initiation in Malawi: A cluster-randomised trial.
INDRAVUDH, PP; FIELDING, K; Kumwenda, MK; Nzawa, R; Chilongosi, R; Desmond, N; Nyirenda, R; NEUMAN, M; JOHNSON, CC; Baggaley, R; Hatzold, K; TERRIS-PRESTHOLT, F; CORBETT, EL;
2021
PLoS medicine
Community-based active case-finding interventions for tuberculosis: a systematic review.
BURKE, RM; Nliwasa, M; FEASEY, HR A; Chaisson, LH; Golub, JE; Naufal, F; Shapiro, AE; Ruperez, M; Telisinghe, L; AYLES, H; CORBETT, EL; MacPherson, P;
2021
The Lancet. Public health
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