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Prof David Conway

Professor of Biology

United Kingdom

David conducts research on malaria, particularly involving population genetic, experimental and epidemiological studies of parasites. Based in London, he also works with colleagues in several countries in West Africa, as well as in Malaysia. He currently serves as Associate Dean for Research in the Faculty. He has served as Head of Department and was previously Head of Malaria Research Programme at the MRC Unit in The Gambia where he studied many aspects of the disease in relation to natural infection and transmission. Prior to that has also worked on other infectious diseases including trachoma and strongyloidiasis. He studied at the University of Nottingham and University of Edinburgh, and worked at Imperial College London before joining LSHTM.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Vaccine Centre

Teaching

Module Organiser for Pathogen Genomics (MSc Module 3460)

Research

Malaria, Parasite Biology, Genomics, Epidemiology, Population Genetics

Research Area
Genetics
Genomics
Epidemiology
Immunology
Disease and Health Conditions
Malaria
Country
Ghana
Gambia
Senegal
Nigeria
Mali
Guinea
Guinea-Bissau
Mauritania
Malaysia
Region
Sub-Saharan Africa (developing only)
East Asia & Pacific (developing only)

Selected Publications

Plasmodium falciparum Sexual Commitment Rate Variation among Clinical Isolates and Diverse Laboratory-Adapted Lines.
STEWART, LB; FREVILLE, A; Voss, TS; BAKER, DA; Awandare, GA; CONWAY, DJ;
2022
Microbiology spectrum
Highly Variable Expression of Merozoite Surface Protein MSPDBL2 in Diverse Plasmodium falciparum Clinical Isolates and Transcriptome Scans for Correlating Genes.
Hocking, SE; STEWART, LB; FREVILLE, A; Reid, AJ; Tarr, SJ; TETTEH, KK A; Flueck, C; Ahouidi, AD; AMAMBUA-NGWA, A; Diakite, M; Awandare, GA; CONWAY, DJ;
2022
mBio
Malaria protection due to sickle haemoglobin depends on parasite genotype.
Band, G; Leffler, EM; Jallow, M; Sisay-Joof, F; Ndila, CM; Macharia, AW; Hubbart, C; Jeffreys, AE; Rowlands, K; Nguyen, T; Gonçalves, S; Ariani, CV; Stalker, J; Pearson, RD; Amato, R; Drury, E; Sirugo, G; D'ALESSANDRO, U; BOJANG, KA; Marsh, K; Peshu, N; Saelens, JW; Diakité, M; Taylor, SM; CONWAY, DJ; ... Kwiatkowski, DP.
2021
Nature
A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures.
Tintó-Font, E; Michel-Todó, L; Russell, TJ; Casas-Vila, N; CONWAY, DJ; Bozdech, Z; Llinás, M; Cortés, A;
2021
Nature microbiology
Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites.
STEWART, LB; Diaz-Ingelmo, O; Claessens, A; Abugri, J; Pearson, RD; Goncalves, S; Drury, E; Kwiatkowski, DP; Awandare, GA; CONWAY, DJ;
2020
COMMUNICATIONS BIOLOGY
Population Genomic Structure and Recent Evolution of Plasmodium knowlesi, Peninsular Malaysia.
Hocking, SE; Divis, PC S; Kadir, KA; Singh, B; CONWAY, DJ;
2020
EMERGING INFECTIOUS DISEASES
Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions.
Georgiadou, A; Lee, HJ; Walther, M; Van Beek, AE; Fitriani, F; Wouters, D; Kuijpers, TW; Nwakanma, D; D'ALESSANDRO, U; Riley, EM; Otto, TD; Ghani, A; Levin, M; Coin, LJ; CONWAY, DJ; Bretscher, MT; Cunnington, AJ;
2019
Nature microbiology
Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum.
TARR, SJ; Díaz-Ingelmo, O; STEWART, LB; Hocking, SE; Murray, L; Duffy, CW; Otto, TD; Chappell, L; Rayner, JC; Awandare, GA; CONWAY, DJ;
2018
BMC GENOMICS
Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development.
Duffy, CW; AMAMBUA-NGWA, A; Ahouidi, AD; Diakite, M; Awandare, GA; Ba, H; Tarr, SJ; MURRAY, L; STEWART, LB; D'ALESSANDRO, U; Otto, TD; Kwiatkowski, DP; CONWAY, DJ;
2018
Scientific reports
Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria.
Lee, HJ; Georgiadou, A; Walther, M; NWAKANMA, D; STEWART, LB; Levin, M; Otto, TD; CONWAY, DJ; Coin, LJ; Cunnington, AJ;
2018
Science translational medicine
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