Dr Amaya Bustinduy MD MPH PhD FRCPCH
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Amaya trained in paediatrics and infectious diseases in the US and started working on helminthic infections, mainly schistosomiasis, and their impact on child health in Coastal Kenya in 2009. She is foremost a field clinical epidemiologist and has investigated a broad range of disease manifestations in children related to parasitic diseases including anaemia, malnutrition, decreased physical performance, decreased quality of life , advanced hepatosplenic disease with a special interest in developing and validating diagnostic and morbidity metric tools at the point-of-care. Other work has included profiling pro-inflammatory cytokines in schistosomiasis and drug (praziquantel) efficacy, particularly in young children.
After moving to the UK, she worked with the Liverpool of Tropical Medicine in Lake Albert Uganda testing novel morbidity point-of-care tests and the first PK/PD study of praziquantel in children. Results of that study are bound to change dosing recommendations for children living with schistosomiasis.
Amaya has been involved in teaching at the East African DTM&H since 2013 and is now the deputy director of the course since 2016 as well as teaching at the Liverpool and London DTM&H regularly.
She has supervised MSc students in the field of parasitic diseases at the LSTM and for MSc Global Health and Tropical paediatric students at the LSTM.
She holds regular teaching sessions for medical students and junior doctors at King's College, St George's University and different NHS trusts.
- Female genital schistosomiasis-new diagnostics at a community level
- Clinical trials involving Pk/PD of antiparasitic drugs in children
- Point-of-care diagnostics for schistosomiasis (infection and morbidity)
- HIV-schistosomiasis and other helminthic co-infection and their impact on child health
- Preschool schistosomiasis and integration of treatment into the Integrated management of childhood illnesses (IMCI)
- Environmental enteropathy in relation to helminthic diseases
- Adolescent health
- Child health
- Clinical trials
- Global Health
- Operational research
Disease and Health Conditions
- Infectious disease
- Lymphatic filariasis
- Neglected Tropical Diseases (NTDs)
- neglected tropical diseases
Point-of-Care Ultrasound Assessment of Tropical Infectious Diseases--A Review of Applications and Perspectives.
Bélard, S. ; Tamarozzi, F. ; Bustinduy, A.L. ; Wallrauch, C. ; Grobusch, M.P. ; Kuhn, W. ; Brunetti, E. ; Joekes, E. ; Heller, T. ;
Am J Trop Med Hyg, 2016; 94(1):8-21
Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy.
Bustinduy, A.L. ; Waterhouse, D. ; de Sousa-Figueiredo, J.C. ; Roberts, S.A. ; Atuhaire, A. ; Van Dam, G.J. ; Corstjens, P.L. ; Scott, J.T. ; Stanton, M.C. ; Kabatereine, N.B. ; Ward, S. ; Hope, W.W. ; Stothard, J.R. ;
MBio, 2016; 7(4)
Expanding Praziquantel (PZQ) Access beyond Mass Drug Administration Programs: Paving a Way Forward for a Pediatric PZQ Formulation for Schistosomiasis.
Bustinduy, A.L. ; Friedman, J.F. ; Kjetland, E.F. ; Ezeamama, A.E. ; Kabatereine, N.B. ; Stothard, J.R. ; King, C.H. ;
PLoS Negl Trop Dis, 2016; 10(9):e0004946
Colley, D.G. ; Bustinduy, A.L. ; Secor, W.E. ; King, C.H. ;
Lancet, 2014; 383(9936):2253-64
HIV and schistosomiasis co-infection in African children.
Bustinduy, A. ; King, C. ; Scott, J. ; Appleton, S. ; Sousa-Figueiredo, J.C. ; Betson, M. ; Stothard, J.R. ;
Lancet Infect Dis, 2014; 14(7):640-9
Impact of polyparasitic infections on anemia and undernutrition among Kenyan children living in a Schistosoma haematobium-endemic area.
Bustinduy, A.L. ; Parraga, I.M. ; Thomas, C.L. ; Mungai, P.L. ; Mutuku, F. ; Muchiri, E.M. ; Kitron, U. ; King, C.H. ;
Am J Trop Med Hyg, 2013; 88(3):433-40
Fecal occult blood and fecal calprotectin as point-of-care markers of intestinal morbidity in Ugandan children with Schistosoma mansoni infection.
Bustinduy, A.L. ; Sousa-Figueiredo, J.C. ; Adriko, M. ; Betson, M. ; Fenwick, A. ; Kabatereine, N. ; Stothard, J.R. ;
PLoS Negl Trop Dis, 2013; 7(11):e2542
Measuring fitness of Kenyan children with polyparasitic infections using the 20-meter shuttle run test as a morbidity metric.
Bustinduy, A.L. ; Thomas, C.L. ; Fiutem, J.J. ; Parraga, I.M. ; Mungai, P.L. ; Muchiri, E.M. ; Mutuku, F. ; Kitron, U. ; King, C.H. ;
PLoS Negl Trop Dis, 2011; 5(7):e1213
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