Matthew Burton PhD MA DTM&H MRCP FRCOphth

Senior Lecturer

• Affiliation
• Publications

• 
• Room 383b
• LSHTM
• Keppel Street
• London
• WC1E 7HT
• T: +44 (0)20 7927 2116

Matthew Burton is an ophthalmologist. He qualified in medicine from Cambridge University in 1994. His post-graduate training has been in Oxford (Adult Medicine and Ophthalmology) and at Moorfields Eye Hospital, London. From 2001 to 2004 he worked as a clinical research fellow at the LSHTM on a Wellcome Trust funded trachoma research programme based at the MRC Laboratories in The Gambia. This involved a range of projects on the control and pathogenesis of trachoma. Studies included: a five-year study of mass azithromycin treatment using quantitative measures of infection, studies on the conjunctival immuno-fibrogenic response to trachoma, a randomised controlled trial of azithromycin following trichiasis surgery and natural history studies of advanced disease.

Matthew holds a Wellcome Trust Career Development Fellowship to continue his research on the control and pathogenesis of blinding trachoma. He has been based at the Kilimanjaro Centre for Community Ophthalmology, KCMC Hospital, Moshi, Tanzania since 2008. He is a senior lecturer within the International Centre for Eye Health at the LSHTM, and is involved in teaching on the MSc in Community Eye Health and the East African DTM&H in Moshi.

Affiliation

• Faculty of Infectious and Tropical Diseases
• Department of Clinical Research

• Selected publications

• What is causing active trachoma? The role of non-chlamydial bacterial pathogens in a low prevalence setting.

  Burton, M.J. ; Hu, V.H. ; Massae, P. ; Burr, S.E. ; Chevallier, C. ; Afwamba, I.A. ; Courtright, P. ; Weiss, H.A. ; Mabey, D.C. ; Bailey, R.L. ;

  Invest Ophthalmol Vis Sci, 2011;

• Active trachoma is associated with increased conjunctival expression of IL17A and pro-fibrotic cytokines.

  Burton, M.J. ; Ramadhani, A. ; Weiss, H.A. ; Hu, V. ; Massae, P. ; Burr, S.E. ; Shangali, W. ; Holland, M.J. ; Mabey, D.C. ; Bailey, R.L. ;

  Infect Immun, 2011;

• Innate immune responses and modified extra-cellular matrix regulation characterize bacterial infection and cellular/connective tissue changes in scarring trachoma.

  Hu, V.H. ; Weiss, H.A. ; Ramadhani, A.M. ; Tolbert, S.B. ; Massae, P. ; Mabey, D.C. ; Holland, M.J. ; Bailey, R.L. ; Burton, M.J. ;

  Infect Immun, 2011;

• Surgery versus epilation for the treatment of minor trichiasis in ethiopia: a randomised controlled noninferiority trial.

  Rajak, S.N. ; Habtamu, E. ; Weiss, H.A. ; Kello, A.B. ; Gebre, T. ; Genet, A. ; Bailey, R.L. ; Mabey, D.C. ; Khaw, P.T. ; Gilbert, C.E. ; Emerson, P.M. ; Burton, M.J. ;

  PLoS Med, 2011; 8(12):e1001136

• Absorbable versus silk sutures for surgical treatment of trachomatous trichiasis in ethiopia: a randomised controlled trial.

  Rajak, S.N. ; Habtamu, E. ; Weiss, H.A. ; Kello, A.B. ; Gebre, T. ; Genet, A. ; Bailey, R.L. ; Mabey, D.C. ; Khaw, P.T. ; Gilbert, C.E. ; Emerson, P.M. ; Burton, M.J. ;

  PLoS Med, 2011; 8(12):e1001137

• The conjunctival transcriptome in scarring trachoma.

  Burton, M.J.; Rajak, S.N.; Bauer, J.; Weiss, H.A.; Tolbert, S.B.; Shoo, A.; Habtamu, E.; Manjurano, A.; Emerson, P.M.; Mabey, D.C.; Holland, M.J.; Bailey, R.L.;

  Infect Immun, 2010;

• Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study.

  Burton, M.J.; Holland, M.J.; Makalo, P.; Aryee, E.A.; Alexander, N.D.; Sillah, A.; Faal, H.; West, S.K.; Foster, A.; Johnson, G.J.; Mabey, D.C.; Bailey, R.L.;

  Lancet, 2005; 365(9467):1321-8

• A randomised controlled trial of azithromycin following surgery for trachomatous trichiasis in the Gambia.

  Burton, M.J.; Kinteh, F.; Jallow, O.; Sillah, A.; Bah, M.; Faye, M.; Aryee, E.A.; Ikumapayi, U.N.; Alexander, N.D.; Adegbola, R.A.; Faal, H.; Mabey, D.C.; Foster, A.; Johnson, G.J.; Bailey, R.L.;

  Br J Ophthalmol, 2005; 89(10):1282-8

• → View all Matthew Burton's publications

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