Simon Brooker BA MSc (Econ) DPhil
- LSHTM
- Keppel Street
- London
- WC1E 7HT
- T: +44 (0) 207 927 2614
- F: +44 (0) 207 927 2918
I am a Wellcome Trust Research Career Development Fellow, currently hosted by the KEMRI-Wellcome Trust Collaborative Programme in Nairobi, Kenya.
I lead a group of epidemiologists interested in the epidemiology and control of parasitic diseases in sub-Saharan Africa, with a focus on the spatial epidemiology of neglected tropical diseases, the targeting of cost-effective control strategies, the burden and control of malaria in schools, and Plasmodium-helminth coinfection. In this work, our group integrates robust spatial and economic statistical methods with substantive field research to address questions of practical public health relevance. We place a strong emphasis on developing an evidence base that can be used by policy makers and programme implementers, and close involvement with national control programmes and international agencies helps promote the effective translation of research findings into practical action.
I have a first degree in Human Sciences and a doctorate in Infectious Disease Epidemiology from the University of Oxford, and a Master's in Health Economics from City University, London. Before joining LSHTM in 2002, I held research appointments at the University of Oxford and Imperial College, London, and I have lived and worked in Ghana, Kenya and Uganda.
I am deputy editor of the open access journal, PLoS Neglected Tropical Diseases.
Affiliation
Teaching
I co-organize (with Jon Cox) the study unit Spatial Epidemiology in Public Health, and sit on the exam board for the MSc Control of Infectious Diseases. I also contribute to a number of other study units, including Parasitology and Entomology and Disease Agents and their Control.
I currently supervise five PhD students: Carol Gitonga (the burden of malaria among Kenyan school children); Ruth Ashton (school-based malaria surveillance in Ethiopia); and Katherine Halliday (school-based malaria control); Jennifer Smith (spatial epidemiology of trachoma); Stella Kepha (plasmodia-helminth interactions).
Research
Our research is supported by grants from the Wellcome Trust, the Bill and Melinda Gates Foundation, the World Bank, International Initiative for Impact Evaluation, and GlaxoSmithKline, and focuses on three main areas:
Global Atlas of Helminth Infection. Information about the distribution of helminth infection is central to the effectiveness of control efforts. We are developing a global atlas to help define the number of individuals at risk of infection and to determine areas requiring mass treatment. Our overall goal is to develop an open-access, global information resource on the distribution of soil-transmitted helminth infections and schistosomiasis: This Wormy World
Malaria control in school children in Africa. Malaria control in Africa has traditionally focused on pre-school children and pregnant women, but as transmission intensity declines school-aged children will become an important risk group, warranting intervention. To help address this issue, we are conducting a range of studies in east and west Africa, including a large-scale cluster randomised controlled trial of intemittent screening and treatment for malaria in 101 schools on the Kenyan coast. This multi-disciplinary project is investigating the health and educational benefits of malaria prevention: Health and Literacy Intervention project.
Epidemiology of malaria-helminth co-infection. Individuals living in the tropics are simultaneously infected with a variety of parasites, including malaria and helminths. Yet little is known about which individuals are most at-risk of co-infection, where they live and what factors determines co-infection. To address this, we are conducting a range of field studies in East Africa investigating the epidemiology of co-infection and its consequences for health.
Research areas
- Disease control
- Economic evaluation
- Helminths
- Parasites
- Surveillance
Disciplines
- Economics
- Epidemiology
- GIS/Spatial analysis
- Operational research
Disease and Health Conditions
- Infectious disease
- Malaria
Regions
- Sub-Saharan Africa (developing only)
Countries
- Ethiopia
- Kenya
- Uganda
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Selected publications
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Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa.
Brooker, S.J. ; Pullan, R.L. ; Gitonga, C.W. ; Ashton, R.A. ; Kolaczinski, J.H. ; Kabatereine, N.B. ; Snow, R.W. ;
J Infect Dis, 2012; 205(5):841-52
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Optimisation of mass chemotherapy to control soil-transmitted helminth infection
Anderson, R.; Hollingsworth, T.D.; Truscott, J.; Brooker, S.
Lancet, 2012; 379(9813):289-290
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Heterogeneities and Consequences of Plasmodium Species and Hookworm Coinfection: A Population Based Study in Uganda.
Pullan, R.L.; Kabatereine, N.B.; Bukirwa, H.; Staedke, S.G.; Brooker, S.;
J Infect Dis, 2011; 203(3):406-17
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Spatial modelling of soil-transmitted helminth infections in kenya: a disease control planning tool.
Pullan, R.L. ; Gething, P.W. ; Smith, J.L. ; Mwandawiro, C.S. ; Sturrock, H.J. ; Gitonga, C.W. ; Hay, S.I. ; Brooker, S. ;
PLoS Negl Trop Dis, 2011; 5(2):e958
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The global atlas of helminth infection: mapping the way forward in neglected tropical disease control.
Brooker, S.; Hotez, P.J.; Bundy, D.A.;
PLoS Negl Trop Dis, 2010; 4(7):e779
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Improving educational achievement and anaemia of school children: design of a cluster randomised trial of school-based malaria prevention and enhanced literacy instruction in Kenya.
Brooker, S.; Okello, G.; Njagi, K.; Dubeck, M.M.; Halliday, K.E.; Inyega, H.; Jukes, M.C.h.;
Trials, 2010; 11:93
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An updated atlas of human helminth infections: the example of East Africa.
Brooker, S.; Kabatereine, N.B.; Smith, J.L.; Mupfasoni, D.; Mwanje, M.T.; Ndayishimiye, O.; Lwambo, N.J.; Mbotha, D.; Karanja, P.; Mwandawiro, C.; Muchiri, E.; Clements, A.C.; Bundy, D.A.; Snow, R.W.;
Int J Health Geogr, 2009; 8:42
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Effect of intermittent preventive treatment of malaria on health and education in schoolchildren: a cluster-randomised, double-blind, placebo-controlled trial.
Clarke, S.E.; Jukes, M.C.; Njagi, J.K.; Khasakhala, L.; Cundill, B.; Otido, J.; Crudder, C.; Estambale, B.B.; Brooker, S.;
Lancet, 2008; 372(9633):127-38
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