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Prof John Ackers

Emeritus Professor

United Kingdom

I worked at the School for many years before retiring in 2006, but remain significantly involved in teaching London-based students. Initially I worked on improved diagnostic methods for Trichomonas vaginalis; later I became interested in other protozoa which infect the mucous-covered surfaces of our bodies, in particular Entamoeba histolytica. I played a modest part in the research which led to the realisation that amoebiasis was caused by two different but, in appearance identical, species of Entamoeba - the truly pathogenic E. histolytica and the harmless E. dispar.

T. vaginalis, for many years neglected, has in recent years attracted research interest as it appears to make transmission of HIV virus more likely, to increase the risk of adverse pregnancy outcomes and, possibly, act as a promoter for carcinoma of the cervix.

Teaching has been central to my career as an academic. Administratively I successively held the posts of Departmental Taught Course Director, School Teaching Programme Director and Distance Learning Co-ordinator and was heavily involved from the beginning in the setting up of the School’s Distance Learning programme as well as the innovative Doctor in Public Health (DrPH) degree.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Teaching

At LSHTM I currently co-organise the Basic Parasitology module, teach on the MSc Medical Parasitology, MSc Control of Infectious Diseases and the Diploma in Tropical Medicine & Hygiene and, externally, on the MSc in Clinical Microbiology at Barts and the London School of Medicine.

I am a member of several LSHTM Examination Boards and a member of the Exam Board for the Royal Veterinary College’s MSc in Veterinary Epidemiology & Public Health. I have conducted PhD vivas for a number of British and overseas Universities.

Research

In 2002 I successfully completed a year's sabbatical taking a Computational Genetics & Bioinformatics MSc course at Imperial College, London. Laboratory research is no longer possible, but I am able to continue with computer-based projects, in collaboration with Dr Derek Huntley and other colleagues at Imperial.

Our main focus up until now has been on exploring the published (but far from finished) E. histolytica and E. dispar genomes and, in particular, trying to understand how two such closely similar organisms can differ in pathogenicity.

I also a particular interest in the families of SINEs (mobile genetic elements) which are present in the genomes of both organisms.

Research Area
Parasitology
Disease and Health Conditions
Trichomoniasis
Neglected Tropical Diseases (NTDs)
Dysentery
Sexually transmitted infections

Selected Publications

Book Review: Amebiasis. Biology and Pathogenesis of Entamoeba
ACKERS, JP;
2016
Frontiers in Microbiology
A preliminary investigation of microsatellite-based genotyping in Trichomonas vaginalis.
Prokopi, M; Chatzitheodorou, T; ACKERS, JP; CLARK, CG;
2011
Transactions of the Royal Society of Tropical Medicine and Hygiene
Bioinformatic analysis of Entamoeba histolytica SINE1 elements.
Huntley, DM; Pandis, I; Butcher, SA; ACKERS, JP;
2010
BMC genomics
Sexual transmission of intestinal parasites in men who have sex with men.
Abdolrasouli, A; McMillan, A; ACKERS, JP;
2009
Sexual health
Ribosomal DNA sequences in the differentiation of pathogenic and non-pathogenic isolates of Entamoeba histolytica.
Cruz-Reyes, JA; Spice, WM; Rehman, T; Gisborne, E; ACKERS, JP;
2009
Parasitology
Structure and content of the Entamoeba histolytica genome.
CLARK, CG; Alsmark, UC M; Tazreiter, M; Saito-Nakano, Y; Ali, V; Marion, S; Weber, C; Mukherjee, C; Bruchhaus, I; Tannich, E; Leippe, M; Sicheritz-Ponten, T; Foster, PG; Samuelson, J; Noël, CJ; Hirt, RP; Embley, TM; Gilchrist, CA; Mann, BJ; Singh, U; ACKERS, JP; Bhattacharya, S; Bhattacharya, A; Lohia, A; Guillén, N; ... Hall, N.
2007
Advances in parasitology
The effects of Entamoeba histolytica lysates on human colonic mucins.
Spice, WM; ACKERS, JP;
2007
The Journal of eukaryotic microbiology
SINE elements of Entamoeba dispar.
Shire, AM; ACKERS, JP;
2007
Molecular and biochemical parasitology
Trichomonas vaginalis infection
MABEY, D; ACKERS, J; Adu-Sarkodie, Y;
2006
Sexually transmitted infections
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