Professor Brendan Wren FRCPath

Head of ITD and Professor of Microbial Pathogenesis and Dean of Faculty of Infectious and Tropical Diseases


Brendan Wren's research interests predominantly involve determining the genetic basis by which bacterial pathogens cause disease. His research group exploits a range of post genome research strategies to gain a comprehensive understanding of how these pathogens function, how they evolve and how they interact with their respective hosts. A core interest includes deciphering the bacterial glycocode and how glycostructures relate to the survival and virulence of bacterial pathogens. An application of this basic research is the development of Protein Glycan Coupling Technology for the production of recombinant glycoproteins. This has been applied for the development of inexpensive glycoconjugate vaccines for human and veterinary use.




Brendan Wren is a member of the board of examiners for the MSc in Medical Microbiology (MM) and also lectures and examines on this course.


Current research focuses on:

Research on individual pathogens include; Clostridium difficileCampylobacter jejuniHelicobacter pyloriBurkholderia pseudomallei, Acinetobacter baumanniiFrancisella tularensisStreptococcus pneumonia, Vibrio cholerae and the enteropathogenic Yersinia.

Campylobacter Resource Facility link.

Research areas

  • Bacteria
  • Vaccines


  • Bacteriology
  • Genetics
  • Genomics
  • Microbiology
  • Molecular biology
  • Pathology

Disease and Health Conditions

  • Diarrhoeal diseases
  • Infectious disease
  • Zoonotic disease


  • East Asia & Pacific (developing only)
  • Europe & Central Asia (all income levels)
  • South Asia
  • Sub-Saharan Africa (developing only)


  • Australia
  • Canada
  • Gambia, The
  • Tanzania
  • Thailand
  • Vietnam
  • Zambia

Other interests

  • Antimicrobial Resistance
  • Bacterial Infections
  • Bacterial Pathogenesis
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