Professor Brendan Wren FRCPath

Professor Microbial Pathogenesis

Brendan Wren's Background

Brendan Wren joined the School with his research team in July 1999. His research interests include determining the genetic basis by which bacterial pathogens cause disease. The research group exploits a range of post genome research strategies to gain a comprehensive understanding of how these pathogens function, how they evolve and how they interact with their respective hosts.

Brendan Wren's Affiliation

Brendan Wren's Teaching

Brendan Wren is a member of the board of examiners for the MSc in Medical Microbiology (MM) and also lectures and examines on this course.

Brendan Wren's Research

Current research focuses on:

1. Bacterial glycosylation and their role in virlunce

2. Exploitation of bacterial glycosylation systems for glycoengineering and novel vaccine design

3. Comparative phylogenomics and the evolution of bacterial virulence

Research on individual pathogens include; Clostridium difficileCampylobacter jejuniHelicobacter pyloriBurkholderia pseudomalleiStreptococcus pneumonia, Vibrio cholerae and the enteropathogenic Yersinia.

Campylobacter Resource Facility link.

Research areas

  • Bacteria
  • Vaccines


  • Bacteriology
  • Genetics
  • Genomics
  • Microbiology
  • Molecular biology
  • Pathology

Disease and Health Conditions

  • Diarrhoeal diseases
  • Infectious disease
  • Zoonotic disease


  • East Asia & Pacific (developing only)
  • Europe & Central Asia (all income levels)
  • South Asia
  • Sub-Saharan Africa (developing only)
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